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36 results about "Selenium enriched yeast" patented technology

Selenium Yeast Basics. Selenium yeast is produced using the microorganism Saccharomyces cerevisiae, which is better known as baker's yeast or brewer's yeast. When the yeast is grown in a selenium-enriched medium, it absorbs the selenium and converts it into the form of selenium naturally found in foods, selenomethionine.

Probiotic composition for improving immunity and preparation method thereof

The invention provides a probiotic composition for improving immunity and a preparation method thereof, and belongs to the technical field of probiotics. The preparation method comprises the following steps: fermenting selenium-enriched nostoc sphaeroides through selenium-enriched saccharomycetes to extract selenium-enriched nostoc sphaeroides polysaccharide and selenium-enriched nostoc sphaeroides protein peptide, mixing with traditional Chinese medicine polysaccharide obtained by extracting astragalus membranaceus, rhodiola rosea, codonopsis pilosula and pseudo-ginseng, and reacting with ferric salt to prepare a polysaccharide-Fe / selenium compound; solid residues are mixed and fermented, and active protein peptide is prepared from the solid residues and selenium-rich nostoc sphaeroides protein peptide; the probiotic composition capable of improving immunity is prepared by extracting a polysaccharide-Fe / selenium compound and a polysaccharide-Fe / selenium compound through an organic solvent, extracting a permeate through an organic solvent to obtain an active component, collecting a bacterial liquid, mixing and embedding the bacterial liquid in the polysaccharide-Fe / selenium compound and sodium alginate, and uniformly mixing the bacterial liquid with the active protein peptide, the active component, taurine and ginsenoside Rg3, so that the probiotic composition capable of improving immunity can play good anti-inflammatory, anti-oxidation, immunoregulation, anti-tumor, anti-virus and other roles, and has a good application prospect. Wide application prospects are realized.
Owner:余昭军

Optimized formula of plant organic nano-selenium for activating immune system, inhibiting cancer cell proliferation, preventing cancers, preventing tumors, resisting oxidation and resisting aging

The invention discloses an optimized formula of plant organic nano-selenium for activating an immune system, inhibiting cancer cell proliferation, preventing cancers, preventing tumors, resisting oxidation and resisting aging, and belongs to the technical field of functional food formulas. According to the formula, selenium-enriched yeast and dl-alpha-tocopheryl acetate are used as main materials, L-ascorbic acid can be selectively added, auxiliary materials such as microcrystalline cellulose and starch sodium octenylsuccinate are matched to prepare a capsule preparation, and the content of functional components in a single preparation is precisely controlled as follows: 90-100 micrograms of selenium and 40-50 mg of vitamin E, or 90-100 micrograms of selenium, 40-50 mg of vitamin E and 40 mg of vitamin C. According to the invention, synergistic interaction is realized through scientific proportioning of functional components, a fat-soluble and water-soluble dual anti-oxidation system is constructed, an organism immune system can be effectively activated, cancer cell proliferation can be inhibited, and meanwhile, the composition has multiple effects of preventing cancers, preventing tumors, resisting oxidation and resisting aging; the preparation method is simple and convenient in process, easy in parameter control and suitable for industrial large-scale production, the prepared preparation is high in active ingredient stability, excellent in bioavailability, high in safety and capable of being widely applied to preparation of related functional foods, and all raw materials are food-grade. The technical problems that an existing selenium compound formula is unreasonable in proportion, poor in efficacy synergy and poor in preparation performance are solved.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

Anti-radiation organic selenium salt as well as preparation method and application thereof

The invention discloses an anti-radiation organic selenium salt and a preparation method and application thereof in the field of functional food additives. The anti-radiation organic selenium salt is prepared from the following components in percentage by weight: basic salt: 80-95% of lake salt, rock salt, bamboo salt, sea salt or refined table salt; the organic selenium active ingredients comprise 0.1 to 2 percent of L-selenomethionine, and / or 1 to 3 percent of selenium-enriched yeast extract, and / or 0.5 to 2 percent of selenized carrageenan. Through fluidized bed coating and microcapsule technologies, the six-month selenium retention rate is greater than or equal to 95%, the problem that organic selenium is easy to degrade is solved, the stability is high, L-selenomethionine and vitamin E cooperate, and simulated digestion experiments show that the selenium bioavailability is greater than or equal to 80% and is superior to that of inorganic selenium (lt); 50%); the organic selenium scavenges free radicals, the vitamin E protects cell membranes, and the zinc and the astragalus extract enhance immunity, so that all-around radiation protection is realized; the amino acid mixture covers the bitter taste of the organic selenium, the delicate flavor score is greater than or equal to 7.5 / 10, and the palatability is good; the method can be directly integrated to an existing salt production line, and is suitable for industrial production.
Owner:ZHONGZHAOKE SALT IND (SHENZHEN) GRP CO LTD

Blueberry anthocyanin nutrient solid composition for relieving eye discomfort

This invention discloses a blueberry anthocyanin nutritional solid composition for relieving eye discomfort. The composition comprises blueberry anthocyanin solid powder, algal oil powder, zinc gluconate, and selenium-enriched yeast, and may optionally contain lipid nutrients containing gamma-linolenic acid, as well as food additives and excipients. Oral administration of this composition provides the body with various nutritional supports related to ocular surface function and ocular moisture, helping to maintain tear secretion levels, improve tear film stability, and support the normal physiological state of the corneal epithelium, thereby relieving eye dryness and discomfort caused by environmental stimuli or increased eye strain. Animal experiments showed that after 14 days of continuous administration of the composition, experimental mice exhibited a significantly increased tear secretion volume compared to the control group without the composition, with an increase of approximately 165%. Corneal fluorescein staining scores were also significantly reduced, indicating improved ocular surface condition and significantly enhanced eye comfort.
Owner:ZHEJIANG LANMEI BIOTECHNOLOGY CO LTD

Black fungus antihypertensive peptide culture medium composition based on selenium-enriched yeast protein, liquid fermentation method and antihypertensive application of black fungus antihypertensive peptide culture medium composition

The invention relates to the technical field of biological medicine and food fermentation, in particular to a black fungus antihypertensive peptide culture medium composition based on selenium-enriched yeast protein, a liquid fermentation method and antihypertensive application of the black fungus antihypertensive peptide culture medium composition. The culture medium comprises selenium-enriched yeast protein, glucose, fermented soybean water extract dregs, inorganic salt and trace elements, the high-activity antihypertensive peptide is obtained by optimizing a liquid fermentation and separation purification process, the ACE inhibition IC50 value of the high-activity antihypertensive peptide is smaller than 50 micrograms per milliliter, and the high-activity antihypertensive peptide can be compounded with a hawthorn extract and the like to prepare an oral preparation and has a remarkable antihypertensive function.
Owner:INST OF MICROBIOLOGY HEILONGJIANG ACADEMY OF SCI

Oligosaccharide selenium ganoderma lucidum capsule capable of enhancing immunity and inhibiting tumors and preparation method of oligosaccharide selenium ganoderma lucidum capsule

The invention belongs to the technical field of health-care products, and discloses an oligosaccharide selenium ganoderma lucidum capsule for enhancing immunity and inhibiting tumors and a preparation method, and the content of the capsule is prepared from the following raw materials in parts by mass: 150-160 parts of collagen, 80-85 parts of chitosan oligosaccharide, 110-130 parts of ganoderma lucidum extract, 45-55 parts of selenium-enriched yeast, 50-80 parts of maltodextrin and 7-10 parts of magnesium stearate. The skin barrier can be improved, intercellular communication can be promoted and local immune response can be stimulated through low-molecular peptide of collagen, intestinal flora balance can be adjusted through chitosan oligosaccharide, probiotic growth can be promoted, mucous membrane immunity can be further improved, and finally immune cells can be effectively activated through polysaccharide and triterpenoids in the ganoderma lucidum extract, so that the immunity of a human body is improved. The activity of macrophages and natural killer cells is enhanced, and the multi-target and multi-path immune regulation effect can effectively enhance the defense of the body to pathogenic microorganisms.
Owner:SHANDONG WEIKANG BIOMEDICAL TECH CO LTD

Biomass saline-alkali soil modifier and preparation method thereof

The invention discloses a biomass saline-alkali soil improver and a preparation method thereof, and relates to the technical field of soil improvement. The fertilizer comprises the following raw materials in parts by weight: 25-35 parts of plant straw compost, 10-15 parts of soybean meal, 15-20 parts of iron modified biomass charcoal, 12-18 parts of humic acid, 3-5 parts of selenium-enriched yeast powder, 8-12 parts of a magnetic bentonite-based nano cellulose composite material, 2-4 parts of a composite salt-tolerant microalgae composition, 5-8 parts of desulfurized gypsum and 2-4 parts of a water-retaining agent. The raw materials are uniformly mixed to obtain the biomass saline-alkali soil modifier. The biomass saline-alkali soil modifier provided by the invention effectively realizes efficient, stable and sustainable improvement of saline-alkali soil.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Organic selenium-rich yeast, its preparation method, product and application

The application relates to organic selenium-rich yeast, a preparation method and products and applications thereof. The organic selenium-rich yeast is prepared by step-by-step expansion culture, fermentation culture, collection of yeast cells and drying, wherein the fermentation culture takes organic starch hydrolysis sugar, organic plant protein enzymolysis liquid and selenium-rich yeast extract as a culture medium. In the organic selenium-rich yeast, the proportion of selenomethionine form selenium in the total selenium weight is greater than 80%, even greater than 90%, the proportion of organic selenium in the total selenium weight is greater than 99%, the total selenium content is 800-2100 ppm, the absorption and utilization rate of the yeast to selenium can reach more than 95%, and the absorption and utilization rate and conversion rate in feeding and food are high. Organic starch and organic plant protein are used as culture medium raw materials, the organic raw material usage is more than 95%, and the organic product certification requirements can be met.
Owner:ANGEL YEAST CO LTD +1

Selenium-rich condiment as well as preparation method and application thereof

The invention discloses a selenium-rich condiment as well as a preparation method and application thereof, and belongs to the technical field of condiments. The medicinal and edible extract, the selenium-enriched yeast and the active antihypertensive substance are added into the selenium-enriched condiment to form a synergistic system of natural active ingredients, trace elements and targeted antihypertensive substances, so that on one hand, accurate sodium benefiting, diuresis and antihypertensive are realized, on the other hand, the blood vessel function is regulated by virtue of the medicinal and edible ingredients, and meanwhile, the selenium element protects the vascular endothelium; the triple effects are superposed, the blood pressure is more stable and lasting, and the risk of cardiovascular diseases can be reduced; besides, seasoning components such as brewed soy sauce powder and sodium glutamate are added to lay a flavor foundation, the dosage of functional components is strictly controlled, the influence of peculiar smell on the core taste of the seasoning is avoided, the bottleneck that the existing product is preferential in effect and insufficient in flavor is broken through, daily cooking seasoning requirements are met, and consumers can unconsciously realize health intervention in diet. The application scene of medicinal and edible food and selenium-enriched food is expanded.
Owner:YIYANTANG YINGCHENG HEALTH SALT MFG

Nutritional freeze-dried powder for enhancing immunity of cats and preparation method of nutritional freeze-dried powder

The invention discloses immunity-enhancing nutritional freeze-dried powder for cats and a preparation method of the immunity-enhancing nutritional freeze-dried powder, and relates to the technical field of freeze-drying. The preparation method comprises the following steps: taking chicken breast granules, tenebrio molitor powder, hermetia illucens larva powder, chicory root paste, puree of kudzuvine root, puree of broccoli, puree of blueberry, puree of carrot, puree of pumpkin, puree of cranberry, puree of brown algae, puree of chlorella, astragalus membranaceus concentrated solution, bovine colostrum powder, zinc methionine chelate, iron lysine chelate, lactoferrin, mannan oligosaccharide, embedded bifidobacterium lactis powder, docosahexaenoic acid and linoleic acid; uniformly stirring yeast beta-glucan, a rosemary extract, selenium-enriched yeast, coenzyme Q10 and natural vitamin E, and performing high-pressure homogenization to obtain slurry; forming the slurry through a brace, an extrusion device or a scraping die to obtain formed slurry; performing ultrasonic treatment on the formed slurry; gradient boosting and constant pressure are carried out; freezing and thawing; performing pre-freezing; performing vacuum freeze drying; after the drying is finished, slowly introducing dry and sterile nitrogen; and screening, carrying out quality inspection, sub-packaging and sealing to obtain the immunity-enhancing nutrient freeze-dried powder for cats.
Owner:QINGDAO MINGYUE ANXIN NUTRITION TECH CO LTD

Selenium-enriched yeast and preparation method thereof

The invention belongs to the technical field of fermentation, and particularly relates to selenium-enriched yeast and a preparation method thereof. The total selenium content in the selenium-enriched yeast is (1500-2500mg / Kg), the organic selenium accounts for more than or equal to 97.0% of the total selenium, and the protein accounts for more than or equal to 51% of the total selenium. The selenium-enriched yeast prepared from saccharomyces cerevisiae is subjected to step-by-step amplification culture, and culture conditions and nutrient solution components are controlled, so that the prepared product is high in total selenium content, high in protein content and good in flavor, the mass percentage of organic selenium in the total selenium also meets the national standard, and meanwhile, compared with a preparation method of baker's yeast, the content of selenium in the product is greatly increased. The preparation method disclosed by the invention is more suitable for production of selenium-enriched yeast, less in material loss and good in economic benefit.
Owner:ZHUHAI TXY BIOTECH HLDG CO LTD

Pet feed additive for enhancing gastrointestinal peristalsis

PendingCN121986880AAntipyreticHydroxy compound active ingredientsBiotechnologyGastrointestinal transit time
The invention discloses a pet feed additive for enhancing gastrointestinal peristalsis. A double-layer embedding structure is adopted, wherein the outer layer is a pH response type compound formed by chitosan and sodium alginate, and the effects of stomach protection and intestinal tract targeted slow release are achieved; the core of the inner layer is a compound of resveratrol and inulin and selenium-enriched yeast prepared through biotransformation. The composition has the synergistic effect through multiple target points: the resveratrol is used for regulating intestinal nerves and resisting inflammation, the inulin is used as prebiotics for promoting proliferation of beneficial bacteria, and the organic selenium is used for enhancing the oxidation resistance of intestinal mucosa, so that the gastrointestinal tract peristalsis is comprehensively and safely promoted. Experiments show that the additive can significantly improve the defecation condition, shorten the gastrointestinal transmission time, optimize the intestinal flora and reduce inflammation, and is suitable for being added to pet food needing to improve gastrointestinal motility.
Owner:ZHENTA (SHANDONG) BIOTECHNOLOGY CO LTD

Liver-protecting hangover-alleviating oral soluble film (film candy) and preparation method thereof

The invention provides a liver-protecting alcoholism-relieving oral dissolving film (film candy) and a preparation method thereof, and belongs to the technical field of functional food. The composition comprises 20-50 parts of a radix puerariae extract, 5-15 parts of selenium-enriched ganoderma lucidum powder / ganoderma lucidum extract, 0.1-1 part of a ginger extract, 0.1-1 part of selenium-enriched yeast powder, 40-50 parts of a composite film-forming agent, 3-15 parts of a vegetable oil / fish and shrimp oil penetration enhancer and 0.5-5 parts of a functional auxiliary agent. The preparation method comprises the standardized technological processes of raw material pretreatment, homogenization treatment, step-by-step mixing, vacuum defoaming film-forming paste preparation, coating forming, original three-stage air inlet drying and slitting packaging, and the core innovation point of the preparation method is the original three-stage air inlet drying process, so that the industrial process bottleneck is thoroughly solved. The product disclosed by the invention can be directly taken in the oral cavity without water, can be completely dissolved within 1-5 minutes, the active ingredients are rapidly absorbed through oral mucosa, the gastrointestinal tract first-pass effect is avoided, the product can take effect within 30 minutes, and the product is adaptive to various scene requirements.
Owner:SHANGHAI SUSTAINABILITY RONGSHENG BIOTECHNOLOGY CO LTD

Feed composition for enhancing anti-stress capability of rats and preparation method of feed composition

The invention relates to the technical field of feed compositions, in particular to a feed composition for enhancing anti-stress ability of mice, which comprises a basic nutrition system and an anti-stress function system, the basic nutrition system comprises cereals, a protein source, a fat source, minerals and a vitamin premix; the anti-stress function system comprises immunoregulation polysaccharide, an organic selenium source and a neuroregulation component; the immunoregulation polysaccharide is selected from at least one of astragalus polysaccharide, codonopsis pilosula polysaccharide and lycium barbarum polysaccharide; the organic selenium source is selected from at least one of selenium yeast, selenized carrageenan and selenium-enriched yeast; the neuroregulation component is selected from at least one of gamma-aminobutyric acid, taurine and theanine. By constructing a ternary synergistic system of the immunomodulatory component, the organic selenium source and the neuromodulation component, a three-dimensional anti-stress mechanism of immunological enhancement, antioxidant protection and neuroendocrine regulation is realized, and multiple damage of stress to a mouse body is relieved from the source.
Owner:BEIJING HAVEST FEED MFG CO LTD

Preparation method of nanoscale wall-broken selenium-enriched yeast

The invention discloses a preparation method of nanoscale wall-broken selenium-enriched yeast, and relates to the technical field of food biologication.The preparation method comprises the following steps that selenium-enriched yeast suspension liquid is prepared; the selenium-enriched yeast suspension is subjected to mild local pore pretreatment, and local pores are formed in cell walls; a mixed solution containing amphiphilic molecules is added into the treated suspension liquid, a reaction is carried out under the low-strength shearing condition to form nanosheets, and the amphiphilic molecules comprise beta-cyclodextrin or a derivative thereof; and carrying out stabilizing treatment on the obtained product, and drying to obtain the nano-scale wall-broken selenium-enriched yeast. According to the invention, the nano-scale wall breaking with relatively ordered structure of the cell wall is realized, and the release and absorption efficiency of the selenium component in the gastrointestinal tract can be obviously improved; the wall breaking process is mild, low in temperature and low in shearing, the structural integrity and biological activity of selenium active ingredients are effectively protected, and the retention rate of the active ingredients is remarkably superior to that of a traditional violent wall breaking method.
Owner:CHONGQING SELENIUM HOME BIOTECHNOLOGY CO LTD

Selenium polypeptide with high antioxidant activity as well as preparation method and application of selenium polypeptide

The invention relates to the technical field of extraction of microbial functional components, in particular to selenium polypeptide with high antioxidant activity as well as a preparation method and application of the selenium polypeptide. The selenium polypeptide provided by the invention is a selenium polypeptide substance with more prominent yeast source high biological activity compared with selenium-enriched yeast, the ABTS free radical scavenging rate reaches 65.51-80.23%, the antioxidant activity under the isoconcentration condition is 5.24-6.42 times of that of total selenium polypeptide, 11.99-14.69 times of that of selenium-enriched protein and 11.18-13.69 times of that of the selenium-enriched yeast, the selenium content is 3646.96-4919.69 mg / kg, and the content of selenium in the selenium-enriched yeast is more than that of the total selenium polypeptide. Compared with selenium-enriched yeast, the selenium-enriched yeast has the advantages of high activity and high absorption efficiency, and has a wide application prospect in the aspects of medicine, functional food, cosmetics and the like.
Owner:HEILONGJIANG LINGTAI HEALTH TECH CO LTD

Saccharomycetes preparation for fermenting soybean meal rich in organic selenium as well as preparation method and application of saccharomycetes preparation

PendingCN121930961AFungiFood processingBiotechnologyLachancea fermentati
The invention belongs to the technical field of selenium-enriched yeast preparations, and particularly relates to a yeast preparation for fermenting organic selenium-enriched soybean meal as well as a preparation method and application of the yeast preparation. The fermentation saccharomyces fermenti for fermenting the soybean meal rich in organic selenium is an AKULF01 strain, the preservation number of the fermentation saccharomyces fermenti is CGMCC (China General Microbiological Culture Collection Center) No.7.629, the preservation date of the fermentation saccharomyces fermenti is January 7, 2026, and the fermentation saccharomyces fermenti is used for converting inorganic selenium and increasing the white content of acid-soluble eggs. After soybean meal is fermented by the AKULF01 strain, the content of organic selenium reaches 18.63 mg / kg-19.56 mg / kg, the content of acid-soluble protein reaches 91.8 g / kg-125g / kg, the content of the organic selenium and the content of the acid-soluble protein in the fermented soybean meal are remarkably increased, and the AKULF01 strain can be used for preparing selenium-enriched soybean meal through fermentation.
Owner:ANKANG UNIV

Liver protection capsule and preparation method thereof

The invention provides a liver protection capsule and a preparation method thereof, and belongs to the technical field of liver protection capsule preparation, and the preparation method comprises the following steps: S1, raw material pretreatment; s2, mixing: mixing the sieved glycine with selenium-enriched yeast according to an equivalent incremental method to obtain mixed powder; s3, granulating and drying: spraying purified water into the boiled mixed powder in the boiling granulator in the step S2 as a wetting agent, and granulating; s4, size stabilization and total mixing: sieving the dried particles, and size stabilization; s5, filling and polishing are conducted, specifically, the capsules with qualified filling are polished; s6, sub-packaging: sub-packaging the capsules in the step S5 into oral solid medicinal high-density polyethylene bottles; through a one-step granulation process, the processes of mixing, granulation, drying and the like are integrated in the same boiling granulator to be completed, the independent steps of soft material preparation, wet granulation and transfer in the traditional process are omitted, the production cycle is remarkably shortened, the material loss is reduced, and the production efficiency and the equipment utilization rate are improved.
Owner:SUNFLOWER PHARM GRP (TANGSHAN) BIO-PHARM CO LTD

Selenium-enriched yeast additive for relieving tear stains of pets

The invention belongs to the technical field of functional feed additives for pets, and discloses a selenium-enriched yeast additive for relieving tear stains of pets, the additive takes selenium-enriched yeast as a core effective component, the content of organic selenium in the selenium-enriched yeast is not less than 1000 mg / kg, and the content of organic selenium in the selenium-enriched yeast is not less than 1000 mg / kg. The chrysanthemum extract, the honeysuckle flower extract and the semen cassiae extract are compounded to form an anti-inflammatory heat-clearing component which is used for relieving lacrimal gland inflammation reaction and reducing abnormal tear secretion; meanwhile, L-lysine, taurine, vitamin C and xanthophyll are introduced as nutrition synergistic components, so that the lacrimal gland mucosa conditioning and eye protection effects are enhanced. According to the additive, low-sodium and low-iodine carrier raw materials are further adopted, and a micronization dispersion treatment process is combined, so that the uniformity and palatability of the product in pet feed are improved. Through multiple synergistic effects of antioxidation, anti-inflammation, heat clearing and nutrition regulation, the pet feed can effectively relieve tear stains of pets from the level of nutrition regulation, and is suitable for long-term feeding of pets.
Owner:BEIJING HANZHUOKUN TECH CO LTD

A pig feed for improving slaughter performance and a method for preparing and feeding the same

PendingCN122320131ABiotechnologyNutrition
This invention relates to the field of animal nutrition and feed, and discloses a pig feed for improving slaughter performance, as well as its preparation and feeding method. The preparation method includes: using safflower seeds as raw material, adding rosemary ethanol extract, and then subjecting it to solid-state fermentation with Bacillus subtilis to prepare fermented safflower seed powder with a high proportion of C-9,T-11 conjugated linoleic acid; adding the fermented safflower seed powder, oat β-glucan, and selenomethionine-type selenium-enriched yeast to the basal diet of fattening pigs to formulate a compound feed; and feeding the feed continuously from the time the fattening pigs reach a weight of 60 kg until slaughter. This invention selectively inhibits the secondary catalytic conversion of C-9,T-11 conjugated linoleic acid through rosmarinic acid, preserving the proportion of active configurations in the fermentation product; and extends the effective utilization time window of conjugated linoleic acid in the fattening pig through oat β-glucan; thus achieving a comprehensive improvement in slaughter performance, including reduced backfat thickness, increased intramuscular fat content, and improved carcass grade.
Owner:LIAONING WELLHOPE AGRI TECH

Application of L-selenium methyl selenocysteine in regulating flora to relieve chemotherapy injury

PendingCN121943877AStrong targetingThe mechanism of action is clearOrganic active ingredientsMilk preparationBiotechnologyBacteroides
The invention belongs to the technical field of functional foods and medicines, and particularly discloses application of L-selenium methyl selenocysteine in preparation of a product for targeted regulation of intestinal flora to relieve chemotherapy immune injury. The target regulation is realized by specifically improving the relative abundance of the beneficial bacteria, namely, Bacteroides acdifaciens, in the intestinal tracts of the subject, so that the relative abundance of the beneficial bacteria, namely the Bacteroides acdifaciens, in the intestinal tracts of the subject is improved. Systematic contrast experiments prove that under the condition of equal selenium content, the selenium-enriched milk powder strengthened by taking L-selenium methyl selenocysteine as a unique selenium source has the effect obviously superior to that of contrast milk powder strengthened by selenium-enriched yeast or sodium selenite in the aspect of relieving immunosuppression, intestinal injury and systemic inflammation caused by cyclophosphamide. The core mechanism of the L-selenium methyl selenocysteine is that the L-selenium methyl selenocysteine can be used for efficiently and specifically enriching Bacteroides acdifaciens, and the L-selenium methyl selenocysteine can be used for efficiently and specifically enriching Bacteroides acdifaciens. Based on the discovery, the invention correspondingly provides a selenium-enriched milk powder product with definite targeting property and excellent effects, and a brand new efficient solution is provided for chemotherapy auxiliary nutrition support of tumor patients.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY +1

Use of ganoderma lucidum spore oil and grifola frondosa composition in preparation of preparation for assisting in relieving colorectal cancer

PendingCN122461362ADisease activityBacteroidetes
The application discloses a use of a ganoderma lucidum spore and grifola frondosa composition in preparation of a preparation for assisting in relieving colorectal cancer. The composition comprises ganoderma lucidum spore oil, squalene, grifola frondosa extract, selenium-rich yeast and the like, and is prepared into soft capsules by using a cold preparation method. A mouse model experiment induced by AOM / DSS proves that the soft capsules can significantly relieve weight loss of mice, reduce a disease activity index, improve colon shortening, inhibit expression of inflammatory factors TNF-alpha and IL-6 in serum and colon tissues, reduce intestinal inflammatory reactions, repair colon crypt structure and intestinal mucosal damage, down-regulate expression of a proliferation marker Ki 67, up-regulate expression of an apoptosis marker Caspase-3, induce tumor cell apoptosis, regulate intestinal flora structure, restore relative abundance of Bacteroidetes and Firmicutes, and reverse abnormal increase of Verrucomicrobia. The application can act on the whole process from intestinal polyps, precancerous lesions to colorectal cancer development, is safe and stable, can be taken for a long time, and has high application value.
Owner:JIANMA PHARM (GUANGDONG) CO LTD

Method for screening high-activity selenium-enriched yeast strain based on protein conformation index, yeast protein and application

The invention discloses a method for screening a high-activity selenium-enriched yeast strain based on a protein conformation index, yeast protein and application. Relates to the technical field of food processing. Comprising the following steps: S1, providing a plurality of different yeast strains; s2, respectively culturing the yeast strains in a selenium-containing culture medium and a control selenium-free culture medium to obtain selenium-enriched yeast and control yeast; s3, respectively extracting proteins from the selenium-enriched yeast and the control yeast to obtain selenium-enriched yeast proteins and control yeast proteins; s4, representing and comparing conformational changes of the selenium-enriched yeast protein and the control yeast protein, wherein the conformational changes comprise beta-folding content and surface hydrophobicity; and S5, based on the conformational change, screening out the selenium-enriched yeast protein. According to the method provided by the invention, the problem of screening blindness caused by pure dependence on selenium content indexes in the prior art is solved, and a new technical path is provided for development of high-activity selenium-enriched yeast products.
Owner:WUHAN POLYTECHNIC UNIVERSITY

Selenium source regulation and control method for directionally producing high-value selenium-rich phellinus igniarius mycelium or sporocarp

PendingCN122030183ACultivating equipmentsMushroom cultivationBiotechnologyMedicinal mushroom
The invention discloses a selenium source regulation and control method for directionally producing high-value selenium-rich phellinus igniarius mycelium or sporocarp, and belongs to the technical field of edible and medicinal fungus cultivation and microbial fermentation. The invention provides a target-oriented differential selenium source strategy aiming at the technical contradiction that a single selenium source cannot meet the requirements of different growth stages of phellinus igniarius in the prior art. When the phellinus igniarius mycelium is used as a target product, a fermentation strategy of adding selenium-enriched yeast in the whole process is adopted; when phellinus igniarius sporocarp is used as a target product, a staged strategy is adopted: selenium-enriched yeast is added in a mycelium culture stage, and sodium selenite is added in a sporocarp culture stage. According to the method, the rule that the mycelium stage is adaptive to organic selenium and the sporocarp stage is adaptive to inorganic selenium is defined for the first time, and through accurate stage-selenium source matching, the selenium content, yield and comprehensive quality of the mycelium or the sporocarp are synchronously improved successfully on the premise that mycelium growth is hardly inhibited.
Owner:SHANGHAI ACAD OF AGRI SCI

A selenium-enriched agaricus bisporus composition and a preparation method thereof

1. Invention Title: A composition of selenium-enriched hazel mushroom and its preparation method. 2. Technical Field: This invention relates to the field of edible fungi, and in particular to a composition of selenium-enriched hazel mushroom and its preparation method. 3. Technical Problem to be Solved: The current practical problems in cultivating selenium-enriched hazel mushrooms are low mycelial absorption rate and unstable selenium content in fruiting bodies. This application aims to solve these practical problems. 4. Technical Solution of this Application: This application, through screening bio-based antibacterial agents, unexpectedly discovered that some plants and some traditional Chinese medicines have the effect of improving mycelial absorption rate and stabilizing selenium content in fruiting bodies. Through extensive testing, a composition that improves mycelial absorption rate and stabilizes selenium content was screened. This composition consists of clove, Polygonum multiflorum, corn silk, Gleditsia sinensis, cinnamon, Salvia miltiorrhiza, Gynostemma pentaphyllum, a mixture of whole buckwheat plants, and selenium-enriched yeast. 5. Main Uses: This invention adds rare new varieties of edible fungi to people's practice of a broad food perspective and the construction of a diversified food supply system.
Owner:LIAONING JINLONGYUAN AGRICULTURAL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD

Sugar-free endurance sports food and method for making same

The application discloses a sugar-free endurance sports food and a preparation method thereof. Product raw materials include retinol acetate oil, cholecalciferol oil, dl-alpha-tocopherol acetate oil, thiamine hydrochloride, riboflavin, pyridoxal hydrochloride, L-ascorbic acid, caffeine, taurine, magnesium sulfate, zinc gluconate, selenium-rich yeast, chromium-rich yeast, emulsifier, sweetener, acidity regulator and dietary fiber. The preparation process is prepared by spray drying and mixing of raw materials, and the raw materials include trace nutrients, emulsifiers, sweeteners, acidity regulators and dietary fibers. Modern granulation, embedding and slow-release preparation technologies are utilized to continuously provide nutrition during sports and realize true sugar-free. The raw materials only contain a small amount of Na + , and will not affect the osmotic pressure of the human body, and are more suitable for supplementing endurance sports.
Owner:NANTONG LICHENG BIOLOGICAL ENG CO LTD

A selenium-containing compound vitamin chewable tablet and its preparation method

This invention relates to a selenium-containing compound vitamin chewable tablet and its preparation method, comprising the following raw materials in parts by weight: 10-16 parts selenium-enriched yeast, 25-35 parts L-ascorbic acid, 0.5-1 part vitamin K, 10-20 parts sorbitol, 1-3 parts DL-α-tocopherol acetate, 3-8 parts sodium octenyl succinate starch, 1-5 parts acetylated distarch adipate, 0.7-1.2 parts magnesium stearate, 0.3-0.5 parts potassium citrate, 0.04-0.07 parts steviol glycosides, and 5-10 parts modified silica. This invention improves the crispness and palatability of the chewable tablet by adding acetylated distarch adipate and sodium octenyl succinate starch; the addition of modified silica effectively reduces vitamin attenuation and improves the stability of the components.
Owner:SELENIUM LIFE MEDICAL RES (SHANXI) CO LTD

Three-selenium composition for promoting proliferation of beneficial bacteria and preparation method of three-selenium composition

The invention discloses a three-selenium composition for promoting proliferation of beneficial bacteria and a preparation method thereof, the three-selenium composition is characterized in that the three-selenium composition is prepared from selenoprotein prepared from mulberry leaves, selenium-rich tea leaves and cardamine violifolia as raw materials, nano selenium-rich yeast and L-selenium-methyl selenocysteine, the components of the three-selenium composition are unique in preparation, the three-selenium composition can generate a synergistic interaction effect under a specific ratio, and the composition has a good effect on promoting proliferation of beneficial bacteria. The selenium-enriched yeast is an organic selenium component, the obtained product not only can safely supplement selenium, but also has the effects of promoting proliferation of beneficial bacteria and enhancing immunity, and the technical requirements of symbolic components, pesticide residues and heavy metal content of the product are ensured by adopting an ultrasonic enzymolysis and biotransformation method and a process of nanocrystallizing the selenium-enriched yeast and adsorbing and filtering an extracting solution. The product provided by the invention has the advantages of large market demand, wide market demand, wide application prospect, facilitation of promotion of popularization and application of precise selenium supplement, facilitation of promotion of development of agricultural product planting and processing industry, and substantial social and economic benefits.
Owner:SHANDONG XINXIWANG ECOLOGICAL AGRI TECH CO LTD

Probiotic fermented wind ginger product with enhanced antioxidant activity and preparation process of probiotic fermented wind ginger product

The invention belongs to the technical field of food fermentation, and particularly relates to a probiotic fermented air-dried ginger product with enhanced antioxidant activity and a preparation process thereof, the preparation process comprises the following steps: S1, cutting air-dried ginger into slices to obtain pretreated air-dried ginger; s2, introducing the pCas9-sgRNA recombinant vector into lactobacillus plantarum by adopting an electrotransformation method to obtain an engineering strain with mutated basic groups, performing shaking culture on saccharomyces cerevisiae in a YPD culture medium at 30 DEG C, and mixing the saccharomyces cerevisiae with the lactobacillus plantarum engineering strain according to a weight ratio of 4: 1 to prepare a composite probiotic agent; s3, mixing the pretreated rhizoma zingiberis with an enzymolysis optimized carbon and nitrogen source and an antioxidant synergist, inoculating a composite probiotic agent, and extracting functional components in a fermentation product to obtain an extracting solution; and S4, compounding Arabic gum and maltodextrin according to a weight ratio of 1.5: 2 to obtain a wall material, adding 0.17% of selenium-enriched yeast, dissolving the selenium-enriched yeast in food-grade ethanol to prepare a wall material solution, mixing the extracting solution and the wall material solution according to a weight ratio of 1: 2.9, adding 0.11% of Tween-80, stirring for minutes to form a uniform emulsion, and carrying out spray drying to prepare the microcapsule.
Owner:SHENZHEN HONGXIN HECHUANG TECHNOLOGY CO LTD

A method for preparing iron-zinc-selenium-enriched yeast

This invention discloses a method for preparing iron-zinc-selenium-enriched yeast, comprising the following steps: (1) adding sterilized inorganic iron solution and inorganic zinc solution to sterilized YPD culture medium, so that the Fe in the culture medium is enriched. 2+ The final concentration is 150-300 mg / L, Zn 2+ The final concentration is 100-300 mg / L, and it is stored at 4℃ for later use; (2) The activated yeast is inoculated into the above culture medium at an inoculation rate of 10%, the initial pH of the culture medium is adjusted to 6-8, the rotation speed is 150-200 r / min, the liquid volume is (50-80) mL / 250 mL, and it is cultured at 28-32℃. When the culture reaches 6 h, sterilized inorganic selenium solution is added to the culture medium to make the Se in the culture medium more concentrated. 2+ The final concentration is 15-30 mg / L, and the culture is continued for (24-48) h. The bacterial cells are collected by centrifugation; (3) The collected bacterial cells are washed and dried to obtain iron, zinc and selenium-enriched yeast. This invention prepares a yeast that can simultaneously obtain iron-enriched yeast, zinc-enriched yeast and selenium-enriched yeast. It has a short fermentation cycle, is easy to cultivate, has a simple process, good stability, high conversion rate of organic iron, zinc and selenium, and is easy to process and store.
Owner:GANSU ACAD OF SCI INST OF BIOLOGY