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Troche of chick embryo polysaccharide

A chicken embryo polysaccharide and tablet technology, which is applied in the directions of pill delivery, color/spectral property measurement, drug combination, etc., can solve the problems of lack of effective control methods for cancer, interference with the normal function of the body, unfavorable long-term medication, etc., and is conducive to environmental protection. , Accurate dosage, convenient to take effect

Inactive Publication Date: 2014-09-03
乔民 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Radiotherapy and chemotherapy also have a killing effect on normal cells, which are characterized by poor specificity and huge side effects. While killing tumor cells, they also greatly interfere with the normal functions of the body, which is not conducive to long-term medication
Due to the lack of effective control methods for cancer, the prognosis of patients is extremely poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The preparation of embodiment 1 chicken embryo polysaccharide tablet for oral administration

[0048] Tablet specification: 0.1g / tablet, the preparation quantity is 10000 tablets;

[0049] Weigh 10 g of chicken embryo polysaccharide, 300 g of microcrystalline cellulose, 190 g of sodium stearate, and 500 g of sodium carbonate.

[0050] The preparation method is as follows:

[0051]Extraction of step 1 chicken embryo polysaccharide:

[0052] 1) SPF chicken embryos are cultured for 9-13 days at a constant temperature of 36-38°C.

[0053] 2) Light inspection of the harvested chicken embryos, mark the position of the allantoic cavity, place it for 16 hours at a temperature of 4°C, and then extract live chicken embryos (the color of dead chicken embryos turns black, and the color of live chicken embryos turns red) ) allantoic fluid or chicken embryo culture.

[0054] 3) Extract the allantoic fluid or chicken embryo culture obtained in step 2) using the following purificat...

Embodiment 2

[0071] The preparation of embodiment 2 chicken embryo polysaccharide tablet for oral administration:

[0072] Tablet specification: 0.1g / tablet, the preparation quantity is 10000 tablets;

[0073] Weigh 15g of chicken embryo polysaccharide, 150g of microcrystalline cellulose, 235g of sodium stearate, and 600g of sodium carbonate.

[0074] The preparation method is as follows:

[0075] Extraction of step 1 chicken embryo polysaccharide:

[0076] 1) SPF chicken embryos were cultured for 12 days at a constant temperature of 36-38°C.

[0077] 2) Light inspection of the harvested chicken embryos, mark the position of the allantoic cavity, place it for 18 hours at a temperature of 4°C, and then extract live chicken embryos (the color of dead chicken embryos turns black, and the color of live chicken embryos turns red) ) allantoic fluid or chicken embryo culture.

[0078] 3) Extract the allantoic fluid or chicken embryo culture obtained in step 2) using the following purification...

Embodiment 3

[0095] The preparation of embodiment 3 chicken embryo polysaccharide chewable tablets

[0096] Tablet specification: 0.1g / tablet, the preparation quantity is 10000 tablets;

[0097] Weigh 20 g of chicken embryo polysaccharide, 150 g of low-substituted hydroxypropyl cellulose, 130 g of sodium stearate, 500 g of sodium carbonate, 100 g of sucrose, and 100 g of sorbitol.

[0098] Extraction of step 1 chicken embryo polysaccharide:

[0099] 1) SPF chicken embryos were cultured for 12 days at a constant temperature of 36-38°C.

[0100] 2) Light inspection of the harvested chicken embryos, mark the position of the allantoic cavity, place it for 18 hours at a temperature of 4°C, and then extract live chicken embryos (the color of dead chicken embryos turns black, and the color of live chicken embryos turns red) ) allantoic fluid or chicken embryo culture.

[0101] 3) Extract the allantoic fluid or chicken embryo culture obtained in step 2) using the following purification process:...

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Abstract

The invention relates to a troche of chick embryo polysaccharide. The troche is mainly prepared from the following raw materials in parts by weight: active component: 1-2 parts of chick embryo polysaccharide, and auxiliary materials: 15-30 parts of microcrystalline cellulose or low substituted hydroxy propyl cellulose, 10-30 parts of sodium stearate and 50-70 parts of sodium carbonate. The invention further discloses a preparation method of the polysaccharide troche. The troche of chick embryo polysaccharide prepared by the invention has the advantages of accurate dosage, stable quality, high purity, convenience in administration and the like.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a polysaccharide tablet extracted from chicken embryos. Background of the invention [0002] The report of the World Health Organization shows that in 2008, there were about 12.7 million new cancer patients and 7.6 million cancer deaths in the world, especially in developing countries, where the number of new cancer cases reached 56%. It is estimated that by 2020, the global cancer incidence The rate will increase by 50%, that is, 15 million new cancer patients will be added every year. Not only that, the number of deaths from cancer is also rising rapidly around the world, and this number may increase to 13.2 million in 2030. Therefore, the research on cancer treatment drugs is related to the vital interests of liver cancer patients and the whole society, and has always been a research hotspot in the pharmaceutical industry and has important social significance. [0...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K31/715A61K47/38A61P35/00G01N21/31
Inventor 乔民金莲英
Owner 乔民
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