Chinese medicine composition for treating toxoplasmosisinswine, and preparation method and application thereof

A technology of toxoplasmosis and composition, applied in the field of traditional Chinese medicine, can solve the problems of endangering human health, troublesome intravenous injection, long course of treatment, etc., and achieve the effect of avoiding veterinary drug residues, avoiding social pollution, and formulating reasonable prescriptions

Inactive Publication Date: 2014-08-13
JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the treatment of this disease, sulfa drugs have been used. Although there is a certain effect, the intramuscular injection of sulfa drugs is more irritating to the tissue, while the intravenous injection is more troublesome and the course of treatment is longer
Moreover, sulfa drugs have relatively large side effects on liver and kidney. If the liver and kidney functions of sick animals are not good, sulfa drugs cannot be used. At the same time, long-term use of sulfa drugs can cause some bacteria to develop drug resistance. make it difficult to treat the disease
After the use of sulfa drugs, there are drug residues in animal products, which directly endanger human health

Method used

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  • Chinese medicine composition for treating toxoplasmosisinswine, and preparation method and application thereof
  • Chinese medicine composition for treating toxoplasmosisinswine, and preparation method and application thereof
  • Chinese medicine composition for treating toxoplasmosisinswine, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Prescription: 15 grams of Vitex japonica leaves; 17 grams of yellow skin leaves; 8 grams of chaga; 5 grams of licorice.

[0051] Concrete preparation process is as follows:

[0052] a. Add 3 times the total weight of 4 traditional Chinese medicines in distilled water to the mixed medicinal materials of Vitex chinensis, yellow bark leaves, chaga, and licorice, soak for 24 hours, decoct 3 times, keep for 0.5 hours after each boiling, combine the decoctions and concentrate to a thick concentrate.

[0053] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 60%, stir and mix well, let it settle for 24 hours, filter, recover ethanol from the filtrate, and add 95% ethanol to the liquid after recovering ethanol Adjust the alcohol concentration to 75% with ethanol, stir well, let it settle for 48 hours, filter, recover the ethanol from the filtrate and concentrate until there is no alcohol smell, add 4 times the amount of distilled water to t...

Embodiment 2

[0056] Prescription: 30 grams of Vitex japonica leaves; 26 grams of yellow skin leaves; 12 grams of chaga; 2 grams of licorice.

[0057] a. Add distilled water of 3 times the total weight of 4 traditional Chinese medicines to the mixed medicinal materials of Vitex chinensis, yellow bark leaves, chaga, and licorice, soak for 30 hours, decoct 3 times, keep for 1 hour after each boil, combine the decoctions and dry Concentrate to a thick concentrate.

[0058] b. Add concentration of 95% ethanol to the concentrated solution to adjust the alcohol concentration to 65%, fully stir and mix, precipitate for 48 hours, filter, recycle ethanol from the filtrate, and add 95% ethanol to the liquid after recovering ethanol. When the alcohol concentration of the medicinal solution is 75%, stir well, let it settle for 48 hours, filter, recover the ethanol from the filtrate and then concentrate until there is no alcohol smell, add distilled water twice the amount of the medicinal solution to th...

Embodiment 3

[0061] Recipe: 35 grams of Vitex japonica leaves; 35 grams of yellow skin leaves; 14 grams of chaga; 4 grams of licorice.

[0062] a. Add distilled water 4 times the total weight of the 4 medicinal materials to the mixed medicinal materials of Vitex japonica, yellow bark leaf, Chaga, and licorice, soak for 27 hours, then decoct 3 times, keep for 1 hour after each boiling, combine the decoction and concentrate to Thick concentrate;

[0063] b. Add ethanol with a concentration of 95% to the concentrated solution to adjust the alcohol concentration to 70%, stir and mix well, let it settle for 48 hours, filter, recover ethanol from the filtrate, and add the concentration of the medicinal solution after recovering ethanol to 95% Adjust the ethanol to the alcohol concentration of the medicinal solution to be 80%, stir well, let it stand for 48 hours, filter, recover the ethanol from the filtrate and concentrate it until there is no alcohol smell, add 2 times the weight of the medici...

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Abstract

The invention discloses a Chinese medicine composition for treating toxoplasmosisinswine, and a preparation method and application thereof. The preparation method of the Chinese medicine composition disclosed by the invention comprises the following steps of: decocting four kinds of traditional Chinese medicines consisting of negundo chastetree leaves, Chinese wampee leaves, inonotus obliquus and liquorice by adding distilled water for 1-3 times, mixing decoctions, concentrating to be thick, adding ethanol with the concentration of 90-95% to adjust alcohol concentration to be 60-70%, precipitating, filtering, concentrating filtrate, adding ethanol with the concentration of 90-95% again into the concentrated liquid medicine to adjust alcohol concentration to be 75-80%, precipitating, filtering, concentrating filtrate, refrigerating and precipitating concentrated liquid medicine by adding distilled water, filtering, and concentrating to obtain liquid medicine. The curative rate of the Chinese medicine composition disclosed by the invention on toxoplasmosisinswine is above 85%; and the Chinese medicine composition has the advantages of low side effect and low use amount and is safe and convenient to use and rapid to absorb.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine composition for pigs, a preparation method thereof and the application of the traditional Chinese medicine composition in the preparation of Chinese veterinary medicine for treating swine toxoplasmosis. Background technique [0002] Toxoplasmosis is a zoonotic disease with a wide variety of hosts. Both humans and animals can be infected, but the incidence rate of pigs is relatively high. The pathogen of this disease was not recognized until the 1970s. For the treatment of this disease, sulfa drugs have been used. Although they have a certain effect, the intramuscular injection of sulfa drugs is more irritating to the tissue, while the intravenous injection is more troublesome and the course of treatment is longer. Moreover, sulfa drugs have relatively large side effects on liver and kidney. If the liver and kidney fun...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/85A61P33/02
Inventor 张步彩陶建平蒋春茂贺生中魏宁程汉管远红赵学刚王荣林於敏戴丽红王坤
Owner JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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