Oxytocin nasal spray
A technology of nasal spray and oxytocin, applied in the field of oxytocin nasal spray, can solve the problems of increasing the economic burden of patients, unacceptable to patients with pain, increasing waste of expensive medicinal liquid, etc., and reducing filling equipment. Requirements, mature processing technology, stable source effect
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Embodiment 1
[0035] 1. Prescription (based on 1000 bottles, 0.1ml / spray)
[0036]
[0037] Second, the preparation process:
[0038] 1. Dosing: Weigh the raw and auxiliary materials of the prescription amount into water of 95% of the prescription amount, stir to dissolve, add water to make up the volume, and get ready.
[0039] 2. Filling: Fill the oxytocin aqueous solution prepared above into the attached figure 2 In the spray bottle shown, fill each bottle with 5.0ml, tighten the spray head (0.1ml / spray), that is, the final product is attached Figure 4 .
[0040] 3. Tests of the number of effective sprays and the residual rate of sprays
[0041] Test method: same as comparative example
[0042] Calculation formula: same as comparative example
[0043] The test results are as follows:
[0044] Table 2 embodiment 1 spray test result table
[0045]
[0046] The result calculated according to the above formula is as follows:
[0047] The total amount of liquid medicine in the s...
Embodiment 2
[0051] 1. Prescription (based on 1000 bottles, 0.1ml / spray)
[0052]
[0053] Second, the preparation process:
[0054] 1. Dosing: Weigh the raw and auxiliary materials of the prescription amount into water of 95% of the prescription amount, stir to dissolve, add water to make up the volume, and get ready.
[0055] 2. Filling: Fill the oxytocin aqueous solution prepared above into the attached image 3 In the spray bottle shown, fill each bottle with 5.0ml, tighten the spray head (0.1ml / spray), that is, the final product is attached Figure 5 .
[0056] 3. Tests of the number of effective sprays and the residual rate of sprays
[0057] Test method: same as comparative example
[0058] Calculation formula: same as comparative example
[0059] The test results are as follows:
[0060] Table 3 embodiment 2 spray test result table
[0061]
[0062] The result calculated according to the above formula is as follows:
[0063] The total amount of liquid medicine in the ...
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