Zolmitriptan nasal spray
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 北京天衡药物研究院有限公司
- Publication Date
- 2013-09-11
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
Technical field:
[0001] The invention relates to a zolmitriptan nasal spray, in particular to a zolmitriptan nasal spray using a spray bottle with a volume of 1.2ml. Background technique:
[0002] Zolmitriptan is a second-generation triptan drug, which is a highly selective and potent 5-HT1B / 1D receptor agonist, which stimulates intracranial blood vessels (including arteriovenous anastomosis) and trigeminal nervous system The 5-HT1B / 1D receptors of sensory nerves can constrict intracranial arteries and inhibit the release of neuropeptides after inflammation, thereby alleviating the onset of migraine. It is currently one of the most ideal drugs for treating migraine.
[0003] Zolmitriptan was first marketed abroad (1997) in the form of tablets, the original manufacturer: AstraZeneca, specifications: 2.5mg, 5mg, trade name: Zomig. Advantages of the tablet: the curative effect is clear, and 73% of the patients' migraine can be relieved after 4 hours of administration. Disadva...