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Composition with sleep improving effect as well as preparation method and use of composition

A technology for improving sleep and composition, which is applied in the fields of composition, preparation and application with sleep-improving effect, and can solve problems such as complex chemical composition, different quality and quantity of medicinal ingredients, and differences in medicinal effects or side effects

Active Publication Date: 2013-10-09
SICHUAN ACAD OF CHINESE MEDICINE SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the common sense in the field of traditional Chinese medicine and the in-depth research of the applicant, the chemical composition of these traditional Chinese medicines is complex, and the extracts obtained by different extraction methods are obviously different. Significant differences

Method used

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  • Composition with sleep improving effect as well as preparation method and use of composition
  • Composition with sleep improving effect as well as preparation method and use of composition
  • Composition with sleep improving effect as well as preparation method and use of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Take 500g of Schisandra chinensis (or Schisandra chinensis), add 8 times the amount of water, reflux and decoct for 1 hour, filter, discard the water, dry the dregs in the sun, crush them, and add ethanol-water mixed solvent with 70(v)% alcohol content ( The same below) 9-fold and 8-fold reflux extraction twice, each time for 1 hour, filtered, combined ethanol extracts, recovered under reduced pressure to remove ethanol, the remaining aqueous solution was left to settle, and the supernatant was poured out to obtain the lower precipitate. That is the lignan extract. Take another 600g ganoderma lucidum decoction pieces, add water 12 times and 10 times respectively, reflux decoction twice, each time for 2 hours, filter, combine the water extracts, recover and remove the solvent, and obtain the water extract of ganoderma lucidum. Then take 1500g of Suanzaoren, crush it, add 10 times and 8 times of 70% ethanol to reflux and extract twice, each time for 1-2 hours, combine the...

Embodiment 2

[0027]Take 300g of Schisandra chinensis (or Schisandra chinensis), add 6 times the amount of water, reflux and decoct for 2 hours, filter, discard the water, crush the dregs, add 8 times the amount of 95% ethanol and 8 times the amount of 70% ethanol, and extract twice under reflux , 2 hours each time, filter, combine the ethanol extracts, recover under reduced pressure to remove all ethanol, leave the remaining aqueous solution to settle, pour out the supernatant, and obtain the lower precipitate—lignan extract. Take another 1500g ganoderma lucidum decoction pieces, add water 8 times to reflux and decoct 3 times, each time for 1 hour, filter, combine the water extracts, recover under reduced pressure to remove the solvent, and obtain the water extract of ganoderma lucidum. Then take 1500g of Semen jujuba, crush it, add 6 times of 50% ethanol to reflux extraction for 3 times, each time for 1 hour, combine the ethanol extract, recover under reduced pressure to remove the solvent...

Embodiment 3

[0029] Take 300g of Schisandra chinensis or Schisandra chinensis, add 12 times the amount of water to reflux and decoct for 1 hour, filter, discard the water, dry the dregs, crush them, add 80% ethanol 10 times and 8 times the amount, and reflux twice, each time After 2 hours, filter, combine the ethanol extracts, recover under reduced pressure to remove all ethanol, leave the remaining aqueous solution to settle, pour out the supernatant, and obtain the lower precipitate—lignan extract. Take another 600g of Ganoderma lucidum decoction pieces, add water 15 times to reflux and decoct twice, each time for 2 hours, filter, combine the water extracts, recover under reduced pressure to remove the solvent, and obtain the water extract of Ganoderma lucidum. Then take 1200g of Suanzaoren, crush it, add 12 times of 70% ethanol to reflux and extract twice, each time for 2 hours, combine the ethanol extracts, recover under reduced pressure to remove the solvent, and obtain the alcoholic e...

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Abstract

The invention discloses a composition with a sleep improving effect as well as a preparation method and use of the composition. The composition comprises lignin extract of schisandra chinensis, water extract of lucid ganoderma and alcohol extract of spina date seed, wherein the proportion (in parts by weight) of the extracted materials is as follows: the schisandra chinensis: lucid ganoderma: spina date seed is 1:(1-5):(1-5), wherein the lignin extract of schisandra chinensis is alcohol-water extract of residual decoction dregs after water-refluxing and extracting kadsura longepedunculata or schisandra chinensis decoction; the water extract of lucid ganoderma is water refluxing extract of lucid ganoderma; the extract of the spina date seed is the alcohol-water refluxing extract of the spina date seed. According to the experiments, the composition has a more reasonable medicinal composition combination and is a natural component composition with a better sleep improving effect. The composition, which is used as the active ingredient, and the acceptable supplementary additive component in the drug or the food can respectively form a drug or functional food with the sleep improving effect.

Description

Technical field [0001] The invention involves a composition with improvement of sleep, as well as its preparation methods and the use of drug / functional food. Background technique [0002] Sleep disorders are extremely common, the incidence is very high, and insomnia is the most common sleep problem.Insomnia has a very serious impact on people's lives and social psychology and physiological functions, often manifested as fatigue, drowsiness, disturbance of mood, reduced cognitive function, motion dysfunction, social and interpersonal difficulties, and non -specific physiological functional disorderswait.The survey found that more than one -third of the investigators were sleeping and sleepy during the day during the day.More than 80%of people think that improper sleep will affect the behavior of the day. If you can't work high -quality, it is difficult to make a thoughtful decision, and he has no patience to listen to others.Most people think that bad sleep can cause errors, no p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L1/06A23F3/34A61K36/79A61K36/725A61P25/20A23L33/00A23L21/10
Inventor 张毅易进海李东晓罗先本刘云华白筱璐侯文婕
Owner SICHUAN ACAD OF CHINESE MEDICINE SCI
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