Synthetic method of tri-n-butyl citrate
A technology of tributyl citrate and a synthesis method, which is applied in the preparation of carboxylate, chemical instruments and methods, preparation of sulfonates, etc., can solve the problems of many side reactions, equipment corrosion, complex post-treatment process and the like
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Embodiment 1
[0020] A kind of synthetic method of tributyl citrate, comprises the following steps:
[0021] (1) Esterification: Add 192 parts by weight of anhydrous citric acid and 260 parts by weight of n-butanol into a reaction kettle with a stirring and heating device, heat to 90°C under stirring to completely dissolve the citric acid, then add 6 parts by weight of catalyzer, after the reaction at a temperature of 102°C for 3.5h, the esterification reaction is completed to obtain a reaction solution; the catalyzer is a mixture of sulfamic acid and activated carbon with a weight ratio of 15:1;
[0022] (2) Dealcoholization: The reaction solution obtained in step (1) was dealcoholized under the conditions of vacuum degree of 0.09MPa and temperature of 90°C for 20 minutes to obtain a mixture of tributyl citrate, activated carbon and sulfamic acid. The mixture of n-butanol and water is rectified to obtain n-butanol and recycled to step (1) for use;
[0023] (3) Filtration: The filtrate obt...
Embodiment 2
[0027] A kind of synthetic method of tributyl citrate, comprises the following steps:
[0028] (1) Esterification: Add 192 parts by weight of anhydrous citric acid and 410 parts by weight of n-butanol into a reaction kettle with a stirring and heating device, heat to 95°C under stirring to completely dissolve the citric acid, then add 17 parts by weight of catalyzer, after reacting 3.0h under the condition of 135 ℃ of temperature, esterification reaction finishes, obtains reaction liquid; Described catalyzer is the sulfamic acid and activated carbon mixture that weight ratio is 15:1;
[0029] (2) Dealcoholization: dealcoholize the reaction solution obtained in step (1) under the conditions of vacuum degree of 0.09MPa and temperature of 135°C for 30 minutes to obtain a mixture of tributyl citrate, activated carbon and sulfamic acid. The mixture of n-butanol and water is rectified to obtain n-butanol and recycled to step (1) for use;
[0030] (3) Filtration: The filtrate obtain...
Embodiment 3
[0034] A kind of synthetic method of tributyl citrate, comprises the following steps:
[0035] (1) Esterification: Add 192 parts by weight of anhydrous citric acid and 330 parts by weight of n-butanol into a reaction kettle with a stirring and heating device, heat to 93°C under stirring to completely dissolve the citric acid, then add 12 parts by weight of catalyzer, after reacting for 3.5h at a temperature of 115°C, the esterification reaction is completed to obtain a reaction solution; the catalyzer is a mixture of sulfamic acid and activated carbon with a weight ratio of 15:1;
[0036] (2) Dealcoholization: dealcoholize the reaction solution obtained in step (1) under the conditions of vacuum degree of 0.09MPa and temperature of 110°C for 25 minutes to obtain a mixture of tributyl citrate, activated carbon and sulfamic acid. The mixture of n-butanol and water is rectified to obtain n-butanol and recycled to step (1) for use;
[0037] (3) Filtration: Centrifuge the mixture ...
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