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Capsule for treating senile calcific valvular heart disease and preparation method thereof

A valvular disease and capsule technology, which is applied in the field of treating senile calcific valvular heart disease capsules and its preparation field, can solve the problems of reducing the incidence of cardiovascular events, aggravating stenosis or insufficiency, etc., reducing the types and dosage of drugs, and facilitating the course of treatment. , good compliance effect

Active Publication Date: 2014-02-12
烟台力量知识产权服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the pathological factor of calcification is not fully considered, it is beneficial to improve the symptoms of heart failure, but it is not helpful to prevent further aggravation of stenosis or insufficiency and reduce the incidence of cardiovascular events

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1, the weight ratio of raw materials: 20 parts of persimmon bark, 10 parts of rose fruit, 6 parts of Usnea, 10 parts of Hovenia citrus, 6 parts of incense, 10 parts of horsetail, 10 parts of bobbin, 10 parts of Shixiang 10 parts of August Zha, 2 parts of Gecko, 6 parts of Ganfeng Chai, and 20 parts of Jiaoguya.

[0037] The preparation method of Example 1 is: mix persimmon bark, thorn rose fruit, usnea, hovenia citrus, incense tree, horsetail, bobbin, Shixiang, Augustia, gecko, windwood, and burnt grain buds, add water and decoct , take the filtrate after 30 minutes, add water to the medicinal dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide them into two parts and take them in the morning and evening.

Embodiment 2

[0038] Example 2, the weight ratio of raw materials: 10 parts of persimmon bark, 6 parts of rose fruit, 3 parts of usnea, 6 parts of hovenia, 3 parts of incense, 6 parts of horsetail, 6 parts of bobbin, and 6 parts of Shixiang 6 servings of August Zha, 1 serving of Gecko, 3 servings of Ganfeng Chai, and 10 servings of Jiaoguya.

Embodiment 3

[0039] Example 3, the weight ratio of raw materials: 20 parts of persimmon bark, 10 parts of rose fruit, 6 parts of Usnea, 10 parts of Hovenia citrus, 6 parts of incense, 10 parts of horsetail, 10 parts of bobbin, 10 parts of Shixiang 10 parts of August Zha, 2 parts of Gecko, 6 parts of Ganfeng Chai, and 20 parts of Jiaoguya.

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PUM

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Abstract

The invention discloses a capsule for treating senile calcific valvular heart disease and a preparation method thereof, so as to solve the problem of cardiac valve calcification is difficult to treat. The preparation method is characterized by comprising the following steps: (1) distilling tetrapanax papyriferum, fruit of rosa davurica pall and littleflower stringbush bark and root through water vapor to extract volatile oil for standby, and storing the decoction dregs for standby; (2) crushing gecko and coked rice sprout into fine powder for standby; (3) uniformly mixing persimmon bark, sunglow, poncirus bark, horsetail, filipendula palmata (pall) maxim, fiveleaf akebia fruit and nakedflower beautyberry branchlet and leaf with the decoction dregs obtained in the step 1, extracting the mixture with alcohol for twice, mixing the two alcohol extracting solutions, filtering, recycling ethanol, and concentrating the filtrate to extract at reduced pressure; (4) adding the fine powder obtained in the step 2 in the extract obtained in the step 3, mixing evenly, drying the mixture at 60 DEG C, crushing the mixture into fine powder, adding polysorbate-80 in the mixture to prepare granules, drying, trimming the granules, spraying the volatile oil obtained in the step 1, mixing evenly, and filling a capsule with the mixture to obtain the capsule. Clinical experiments prove that the capsule for treating senile calcific valvular heart disease disclosed by the invention has the advantages of good curative effect and high safety, so that the capsule is worthy of clinical application and popularization.

Description

[0001] technical field [0002] The invention relates to the field of traditional Chinese medicine, in particular to a capsule for treating senile calcific heart valve disease and a preparation method thereof. Background technique [0003] Senile calcific valvular heart disease (SCHVD) mainly refers to the calcification of the connective tissue of the heart valve in the elderly as they age, which leads to abnormal function of the valve or stent. It is a common heart valve disease in the elderly, and it is also one of the important causes of heart failure and sudden death in the elderly. Cardiac echocardiography provides a reliable diagnostic basis for senile calcific valvular heart disease. With the prolongation of human life span, the incidence of calcific valvular heart disease in the elderly increases year by year, and its incidence increases with age, and it is more common in the elderly over 60 to 65 years old. The pathogenesis of the disease is unclear, but it is mor...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/48A61P9/00A61K35/56A61K35/583
Inventor 罗群
Owner 烟台力量知识产权服务有限公司
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