Pharmaceutical composition for treating senile calcific valve disease

A valvular disease and composition technology, which is applied in the field of pharmaceutical composition for the treatment of senile calcific valvular heart disease, can solve problems such as stenosis or insufficiency aggravation, reduce the incidence of cardiovascular events, etc., reduce the types and dosage, increase liver The effect of kidney burden and prevention of cold diarrhea

Inactive Publication Date: 2015-06-10
孙晓峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the pathological factor of calcification is not fully considered, it is beneficial to improve the symptoms of heart failure, but it is not helpful to prevent further aggravation of stenosis or insufficiency and reduce the incidence of cardiovascular events

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1, the weight ratio of raw materials: 20 parts of persimmon bark, 10 parts of rose fruit, 6 parts of Usnea, 10 parts of Hovenia citrus, 6 parts of incense, 10 parts of horsetail, 10 parts of bobbin, 10 parts of Shixiang 10 parts of August Zha, 2 parts of Gecko, 6 parts of Ganfeng Chai, and 20 parts of Jiaoguya.

[0031] The preparation method of Example 1 is: mix persimmon bark, thorn rose fruit, usnea, hovenia citrus, incense tree, horsetail, bobbin, Shixiang, Augustia, gecko, windwood, and burnt grain buds, add water and decoct , take the filtrate after 30 minutes, add water to the medicinal dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide them into two parts and take them in the morning and evening.

Embodiment 2

[0032] Example 2, the weight ratio of raw materials: 10 parts of persimmon bark, 6 parts of rose fruit, 3 parts of usnea, 6 parts of hovenia, 3 parts of incense, 6 parts of horsetail, 6 parts of bobbin, and 6 parts of Shixiang 6 servings of August Zha, 1 serving of Gecko, 3 servings of Ganfeng Chai, and 10 servings of Jiaoguya.

Embodiment 3

[0033] Example 3, the weight ratio of raw materials: 20 parts of persimmon bark, 10 parts of rose fruit, 6 parts of Usnea, 10 parts of Hovenia citrus, 6 parts of incense, 10 parts of horsetail, 10 parts of bobbin, 10 parts of Shixiang 10 parts of August Zha, 2 parts of Gecko, 6 parts of Ganfeng Chai, and 20 parts of Jiaoguya.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating senile calcific valve disease. The pharmaceutical composition is applied to the therapy of cardiac valve calcification. The pharmaceutical composition is characterized by being prepared from the following raw pharmaceutical materials in proportion by weight: Diospyros kaki Thunb., Rosa davurica Pall., Usnea diffracta Vain., Poncirus tuifoliata (L.) Raf., Wikstroemia micrantha Hemsl., Equisetum hiemale L., Gastrodia elata Bl., Bulbophyllum reptans Lindl., Akebia trifoliata Koidz., Gekko gecko Linnaeus, Callicarpa nudiflora Hook. Et Arn. and Setaria italica (L.) Beauv.. Proved by clinical trials, the pharmaceutical composition has the characteristics of good treatment effect and relatively high safety in the therapy of senile calcific valve disease, so that the pharmaceutical composition is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating senile calcific heart valve disease. Background technique [0002] Senile calcific valvular heart disease (SCHVD) mainly refers to the calcification of the connective tissue of the heart valve in the elderly as they age, which leads to abnormal function of the valve or stent. It is a common heart valve disease in the elderly, and it is also one of the important causes of heart failure and sudden death in the elderly. Cardiac echocardiography provides a reliable diagnostic basis for senile calcific valvular heart disease. With the prolongation of human life span, the incidence of calcific valvular heart disease in the elderly increases year by year, and its incidence increases with age, and it is more common in the elderly over 60 to 65 years old. The pathogenesis of the disease is unclear, but it is more common in patients wi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P9/00
Inventor 孙晓峰刘渊王西英
Owner 孙晓峰
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