A capsule for treating senile calcific valvular heart disease and its preparation method

Abstract

The invention discloses a capsule for treating senile calcific valvular heart disease and a preparation method thereof, so as to solve the problem of cardiac valve calcification is difficult to treat. The preparation method is characterized by comprising the following steps: (1) distilling tetrapanax papyriferum, fruit of rosa davurica pall and littleflower stringbush bark and root through water vapor to extract volatile oil for standby, and storing the decoction dregs for standby; (2) crushing gecko and coked rice sprout into fine powder for standby; (3) uniformly mixing persimmon bark, sunglow, poncirus bark, horsetail, filipendula palmata (pall) maxim, fiveleaf akebia fruit and nakedflower beautyberry branchlet and leaf with the decoction dregs obtained in the step 1, extracting the mixture with alcohol for twice, mixing the two alcohol extracting solutions, filtering, recycling ethanol, and concentrating the filtrate to extract at reduced pressure; (4) adding the fine powder obtained in the step 2 in the extract obtained in the step 3, mixing evenly, drying the mixture at 60 DEG C, crushing the mixture into fine powder, adding polysorbate-80 in the mixture to prepare granules, drying, trimming the granules, spraying the volatile oil obtained in the step 1, mixing evenly, and filling a capsule with the mixture to obtain the capsule. Clinical experiments prove that the capsule for treating senile calcific valvular heart disease disclosed by the invention has the advantages of good curative effect and high safety, so that the capsule is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a capsule for treating senile calcific heart valve disease and a preparation method thereof. Background technique [0002] Senile calcific valvular disease (SCHVD) mainly refers to the calcification of the connective tissue of the heart valve as the elderly grow older, resulting in abnormal valve or stent function. It is a common heart valve disease in the elderly and one of the important causes of heart failure and sudden death in the elderly. Cardiac echocardiography provides a reliable diagnostic basis for senile calcific valvular heart disease. With the prolongation of human lifespan, the incidence of senile calcific valvular heart disease is increasing year by year. The pathogenesis of the disease is unclear, but it is more common in patients with pre-existing atherosclerosis, most often on the ventricular surface of the posterior lobe. The evolution of the dis...

AI Technical Summary

Problems solved by technology

Since the pathological factor of calcification is not fully considered, it is beneficial to improve the symptoms of heart failure, but it is not helpful to prevent further aggravation of stenosis or insufficiency and reduce the incidence of cardiovascular events