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Preparation method and application of perillaseed qi depressing pellet

A technique of reducing qi and frying perilla seeds is applied in medical preparations containing active ingredients, devices for making medicines into special physical or taking forms, and pharmaceutical formulations. Impurities and other problems

Inactive Publication Date: 2014-03-26
李梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of supercritical technology in the extraction and preparation of Suzi Jiangqi Pills. However, the method of powdering is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the quality of life. This product is used clinically

Method used

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  • Preparation method and application of perillaseed qi depressing pellet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Take 160g fried perilla seeds, 160g Magnolia officinalis, 160g Peucedanum, 160g licorice, 160g ginger pinellia, 160g tangerine peel, 112g agarwood, 112g angelica and add to CO 2 In a supercritical extractor, ethanol is used as an entrainer, and the entrainer accounts for 4% by volume of the total extraction solvent. The extraction pressure is 15MPa, the temperature is 30°C, and the CO 2 The flow rate is 1m1 / g crude drug·min, and the extraction time is 150min to obtain a supercritical extract, which is crushed into fine powder, and 550g is obtained as a water pill.

Embodiment 2

[0018] Take 160g fried perilla seeds, 160g Magnolia officinalis, 160g Peucedanum, 160g licorice, 160g ginger pinellia, 160g tangerine peel, 112g agarwood, 112g angelica and add to CO 2 In a supercritical extractor, ethanol is used as an entrainer, and the volume percentage of the entrainer in the total extraction solvent is 6%, the extraction pressure is 30MPa, the temperature is 50°C, and the CO 2 The flow rate is 3m1 / g crude drug·min, and the extraction time is 180min to obtain supercritical extract, which is crushed into fine powder, and 550g is obtained as water-flooded pills.

Embodiment 3

[0020] Take 160g fried perilla seeds, 160g Magnolia officinalis, 160g Peucedanum, 160g licorice, 160g ginger pinellia, 160g tangerine peel, 112g agarwood, 112g angelica and add to CO 2 In the supercritical extractor, ethanol is used as an entrainer, and the entrainer accounts for 5% by volume of the total extraction solvent, the extraction pressure is 20MPa, the temperature is 40°C, and the CO 2 The flow rate is 2m1 / g crude drug·min, and the extraction time is 160min to obtain a supercritical extract, which is crushed into fine powder, and 550g is obtained as water-flooded pills.

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PUM

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Abstract

The invention provides a preparation method of a perillaseed qi depressing pellet. The pellet is prepared from 160 g of fried perillaseed, 160 g of mangnolia officinalis, 160 g of common hogfenneI root, 160 g of liquorice, 160 g of ginger processed pinellia, 160 g of dried orange peel, 112 g of agilawood and 112 g of angelica sinensis as raw material medicines through supercritical fluid extraction. Therefore, the content is greatly increased, and the dosage is reduced. The invention further provides application of the perillaseed qi depressing pellet in preparing a medicament for inhibiting cell proliferation of human histocyte lymphoma U937.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a preparation method and application of Suzijiangqi pills. Background technique [0002] Suzi Jiangqi Pills are recorded in the standard WS3-B-0278-90 of the Ministry of Health, and the prescription is 160g of fried perilla seeds, 160g of Magnolia officinalis, 160g of Qianhu, 160g of licorice, 160g of ginger pinellia, 160g of tangerine peel, 112g of agarwood, 112g of angelica, and more Eight flavors, except perilla seeds, the other seven flavors are crushed into fine powder, then grinded together with perilla seeds, sieved, and mixed; use 40g ginger and 80g jujube to fry pan balls; dry at low temperature to get 1100g, that is, . Can reduce qi and resolve phlegm, warm kidney and accept qi. It is used for stagnation of qi against phlegm, cough and wheezing, and stuffy chest septum. [0003] In the prior art, there is no report on the use of supe...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61K9/20A61P35/00A61J3/06
Inventor 李强
Owner 李梅
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