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An intervention drug for postoperative pain in children

A drug and pediatric technology, applied in the direction of drug combination, antipyretics, pharmaceutical formulations, etc., can solve problems such as restrictions on the use of analgesic drugs, and achieve the effect of reducing the expression of NMDA receptors

Inactive Publication Date: 2015-11-11
张迎春
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the special constitution of children, the use of some analgesics in children is restricted

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1, raw material drug weight ratio: 20g of fig leaf, 10g of sarcocarpus, 6g of dendrobium, 10g of kudzu rice, 6g of geese not eating grass, 10g of trichosanthes, 10g of almond, 10g of eucalyptus, 10g of cassia twig, green 2g of fenzi, 6g of papaya, and 20g of dog seedlings.

[0031] The preparation method of Example 1 is: mix fig leaf, sarcophagus, dendrobium, kudzu rice, geese not eating grass, trichosanthes, almond, eucalyptus, osmanthus twig, green scorpion, papaya, dog vine and add water After decocting, take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, and combine the two filtrates. For children weighing >50kg, the above water decoction is divided into two portions and taken in the morning and evening. For children with a body weight of 30-50kg, the above-mentioned decoction is divided into 4 parts and taken in the morning and evening. For children with a body weight of...

Embodiment 2

[0032] Example 2, raw material drug weight ratio: 10 parts of fig leaves, 6 parts of sarcophagus, 3 parts of dendrobium, 6 parts of kudzu rice, 3 parts of goose not eating grass, 6 parts of trichosanthes, 6 parts of almonds, eucalyptus leaves 6 parts, 6 parts of cassia twigs, 1 part of Qingzizi, 3 parts of papaya, and 10 parts of dog seedlings.

Embodiment 3

[0033] Example 3, the weight ratio of raw materials: 20 parts of ficus fig leaves, 10 parts of sarcocarpus, 6 parts of dendrobium, 10 parts of kudzu rice, 6 parts of geese not eating grass, 10 parts of trichosanthes, 10 parts of almonds, eucalyptus leaves 10 parts, 10 parts of cassia twigs, 2 parts of Qingzizi, 6 parts of papaya, and 20 parts of dog seedlings.

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PUM

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Abstract

The invention discloses an intervention drug for child postoperative pain to solve the treatment problem of ABC. The intervention drug is characterized by being prepared from the following raw materials in parts by weight: ficus virens leaves, sarcandra glabra, dendrobium, common nostoc, centipeda minima, trichosanthes kirilowii maxim, almonds, folium eucalypti, cinnamomum cassia presl, celosia argentea seeds, pawpaw and calystegia dahurica roots. A clinical experiment proves that the intervention drug has the characteristics of good treatment effect and higher safety for relieving the postoperative pain, so that the intervention drug is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for intervening postoperative pain in children. Background technique [0002] Pain is a subjective feeling shared by infants and children. At the 25th week of pregnancy, the pain receptors have developed, and the newborn can not only feel pain, but also cause abnormal pain sensation in the future due to insufficient pain treatment. Postoperative pain is an unpleasant sensory and emotional experience caused by surgical trauma. Due to the special constitution of children, the use of some analgesics in children is restricted. For example, improper use of morphine and fentanyl is prone to excessive sedation and respiratory depression. [0003] Moreover, studies in recent years have shown that postoperative pain in children is highly correlated with "postoperative pain hypersensitivity". "Postoperative pain hypersensitivity state" is different from traumatic ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P29/00
Inventor 张迎春陈玲刘明华王春爱
Owner 张迎春
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