Microfluidic microbial culture detection chip
A technology for microbial culture and detection chips, which is applied in the field of microfluidics and can solve the problems of lack of culture liquid detection structure and inability to measure concentration.
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[0030] The microfluidic optical comparison chip of ToddThorsen, etc. can only detect specific fluorescently labeled bacteria, and cannot realize multi-channel bacterial suspension culture on the chip. Suspension culture is a very important step for microbial screening. It provides specific microbial growth conditions and determines the elimination and retention of certain characteristics of strains.
[0031] Although the microfluidic microbial culture chips disclosed in Chinese Patent Nos. CN201110316751.0 and CN201110142095.7 solve the problem of microorganisms being cultured in suspension on the chip, they can only provide indicators of the growth rate of microorganisms and cannot detect changes in the concentration of specific substances in the culture solution Condition. The detection of the concentration of specific substances in the culture medium is an important basis for judging the quality of the strain, and it is very important for the screening of the strain.
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