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Sunset abelmoschus flower general flavone gel for treating dental ulcer and preparation method of gel

A technology of total flavonoid gel and oral ulcer, which is applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve the problem of high irritation and no total flavonoid gel found in hollyhock flowers. Dosage reports, drug unevenness on the ulcer surface, etc.

Inactive Publication Date: 2014-06-25
合肥海大生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This marshmallow flower total flavonoids powder (spray) has many weak points: dosage is big, waste is big, after medication (spray), the medicine of ulcer surface is uneven, and patient often appears to be full of medicine, and irritation is big, and patient tolerance Poor performance; for patients with scattered ulcers, it is even more unacceptable, which makes clinical work difficult and difficult to continue. Now the manufacturer has given up the development
[0005] Did not find any reports about the total flavonoids gel of hollyhock flowers in the patent search

Method used

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  • Sunset abelmoschus flower general flavone gel for treating dental ulcer and preparation method of gel
  • Sunset abelmoschus flower general flavone gel for treating dental ulcer and preparation method of gel
  • Sunset abelmoschus flower general flavone gel for treating dental ulcer and preparation method of gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Take 10g of the total flavonoids powder of hollyhock flower and grind it finely, and set it aside; add 20g of the viscose carbomer and water to make a 2% solution, soak it to make it swell, add triethanolamine to adjust the pH value to 7, then add 30g of moisturizing agent glycerin, transdermal Accelerator Azone 20g, stir evenly to obtain a gel matrix; mix the matrix with fine powder, add water to 1000g, stir evenly, and obtain the total flavonoid gel of hollyhock flower of the present invention.

Embodiment 2

[0062] Take 25g of the total flavonoids powder of hollyhock flowers and grind it finely, and set it aside; add 40g of viscose hydroxypropyl methylcellulose and water to make a 7% solution, soak it to make it swell, then add 100g of humectant polyethylene glycol and skin penetration accelerator 40g of azone, stirred evenly, to obtain a gel matrix; mixed the matrix with fine powder, added water to 1000g, stirred evenly, and obtained the total flavonoid gel of hollyhock flower of the present invention.

Embodiment 3

[0064] Take 20g of the total flavonoids powder of hollyhock flowers and grind it finely, and set it aside; add 32g of viscose sodium hydroxymethyl cellulose to water to make a 4% solution, soak it to make it swell, then add 60g of humectant sorbitol and 31g of transdermal accelerator Azone , stir evenly to obtain a gel matrix; mix the matrix with fine powder, add water to 1000g, and stir evenly to obtain the total flavonoid gel of marshmallow flowers of the present invention.

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PUM

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Abstract

The invention discloses sunset abelmoschus flower general flavone gel for treating dental ulcer. The gel is prepared from sunset abelmoschus flower general flavone (the content of general flavone is 50-90%), an adhesive, a moistening agent and a transdermal enhancer. The invention further discloses a preparation method of the gel. Experiments show that the gel disclosed by the invention is strong in pharmacologic action, free from irritation and few in adverse effect, and has good effects of relieving pain, preventing inflammation and promoting anabrosis to be healed.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a gel of total flavonoids from marshmallow flowers for treating oral ulcers and a preparation method thereof. Background technique [0002] Hollyhock flower is the dried corolla of Malvaceae Abelmoschus manihot (L.) Medi c., which is included in the supplementary edition of "Jiangsu Provincial Standards of Chinese Medicinal Materials" (1989 edition) and "Shandong Provincial Standards of Chinese Medicinal Materials" 2002 edition. It has the effects of clearing dampness and heat, reducing inflammation and detoxification. It is a traditional medicinal plant in my country. The history of its use as medicine can be traced back to 1500 years ago in "The Back of the Elbow" written by Ge Hong in the Jin Dynasty. Gonorrhea, carbuncle, swollen toxin, and burns caused by soup and fire." There are many applications among the people to treat sores, mumps, urin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K47/22A61K9/06A61P1/02
Inventor 徐旭东杜安全周正华
Owner 合肥海大生物医药科技有限公司
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