Injection reagent for cosmetic filling

A technology of reagents and cross-linking agents, applied in the field of cosmetic injection reagents, can solve problems such as being in the blank

Inactive Publication Date: 2014-09-03
白晋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the injection reagents for eliminating facial forehead lines, crow's feet, eyebrow lines, nasolabial lines, and perioral wrinkles are still blank

Method used

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  • Injection reagent for cosmetic filling
  • Injection reagent for cosmetic filling
  • Injection reagent for cosmetic filling

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1: The present invention selects transforming growth factor 13%, platelet-derived growth factor 22%, epidermal growth factor 12%, fibronectin 4%, vitronectin 2%, protease-activated receptor 38%, interleukin 1β 2% , fibrin 2%, vascular endothelial cell growth factor 3% and insulin-like growth factor 2% The test results of the reagent developed are shown in the table below (percentages in this embodiment and the following examples, after the decimal point The value of is rounded to 1 decimal place):

[0012] Analysis of wrinkle curative effect at 3-month follow-up [case (%)]

[0013]

[0014] Analysis of wrinkle curative effect at 6-month follow-up [case (%)]

[0015]

[0016] Analysis of wrinkle curative effect at 9-month follow-up [case (%)]

[0017]

[0018]

[0019] Scar Treatment:

[0020] Scar efficacy analysis at each follow-up [case (%)]

[0021]

[0022] Wrinkle or Scar Satisfaction Rating [Median (25% quantile, 75% quantile)]

[00...

Embodiment 2

[0026] Embodiment 2: The present invention selects transforming growth factor 16%, platelet-derived growth factor 19%, epidermal growth factor 9%, fibronectin 3%, vitronectin 4%, protease-activated receptor 37%, interleukin 1β 2% , fibrin 5%, vascular endothelial growth factor 2% and insulin-like growth factor 3% by weight percentage The test results of the reagent developed are shown in the table below:

[0027] Analysis of wrinkle curative effect at 3-month follow-up [case (%)]

[0028]

[0029]

[0030] Analysis of wrinkle curative effect at 6-month follow-up [case (%)]

[0031]

[0032] Analysis of wrinkle curative effect at 9-month follow-up [case (%)]

[0033]

[0034] Scar Treatment:

[0035] Scar efficacy analysis at each follow-up [case (%)]

[0036]

[0037]

[0038] Wrinkle or Scar Satisfaction Rating [Median (25% quantile, 75% quantile)]

[0039]

[0040] How long does it take for wrinkles or scars to appear?

[0041] wrinkle area...

Embodiment 3

[0042] Embodiment 3: The present invention selects 17% of transforming growth factor, 23% of platelet-derived growth factor, 11% of epidermal growth factor, 2% of fibronectin, 3% of vitronectin, 32% of protease-activated receptor, and 1% of interleukin-1β , fibrin 6%, vascular endothelial growth factor 1% and insulin-like growth factor 4% weight percentages The test results of the reagent developed are shown in the table below:

[0043] Analysis of wrinkle curative effect at 3-month follow-up [case (%)]

[0044]

[0045] Analysis of wrinkle curative effect at 6-month follow-up [case (%)]

[0046]

[0047] Analysis of wrinkle curative effect at 9-month follow-up [case (%)]

[0048]

[0049] Scar Treatment:

[0050] Scar efficacy analysis at each follow-up [case (%)]

[0051]

[0052] Wrinkle or Scar Satisfaction Rating [Median (25% quantile, 75% quantile)]

[0053]

[0054] How long does it take for wrinkles or scars to appear?

[0055] wrinkle area...

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Abstract

The invention relates to an injection reagent for cosmetic filling, and the injection reagent comprises the following ingredients in percentage by weight: 13-17% of transforming growth factor -beta, 19-23% of platelet-derived growth factor, 9-12% of epidermal growth factor, 2-4% of fibronectin, 2-4% of vitronectin, 32-38% of protease-activated receptor, 1-2% of interleukin 1beta and 2-6% of cross-linking agent. The injection reagent for cosmetic filling is capable of removing frontal cross striation, crow feet, intercilium wrinkle, nasolabial wrinkle, perioral wrinkle and scars, and is free of untoward effects and safe to use.

Description

technical field [0001] The invention relates to a cosmetic injection reagent, in particular to an injection reagent used for cosmetic filling to eliminate wrinkles and scars. Background technique [0002] Tissue transplantation is one of the basic contents and treatment methods of plastic surgery research, among which injection transplantation technology conforms to the development trend of modern minimally invasive surgery, especially for plastic surgery patients. The application of injectable tissue materials for non-invasive and non-permanent facial filling has become the most popular operation method, but the research and development of injectable soft tissue filling materials has always been a very challenging topic for plastic and cosmetic surgeons. In recent years, a variety of injectable soft tissue materials, including synthetic and allogeneic and heterologous natural materials, have been widely used. However, the injection reagents for eliminating horizontal foreh...

Claims

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Application Information

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IPC IPC(8): A61L27/54A61L27/26
Inventor 白晋
Owner 白晋
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