A kind of preparation method of collagen suture thread

Abstract

The invention relates to a preparation method of a collagen suture line and belongs to the technical field of medical suture lines. The collagen suture line disclosed by the invention is a novel suture line, is extracted from small intestines of plateau black goats, is subject to processes such as degreasing, inactivation of viruses, rinsing, purification, straightening, screening, oil tanning and sterilization and is finally placed in protection liquid for sealed storage. The preparation method has the beneficial effects that the collagen suture line prepared by the method is stable in property, good in elasticity, high in flexibility, easy to knot and high in tensile strength and can be completely absorbed by a human body without antigen-antibody reaction, needle eyes or scars; a sutured wound is smoothly healed; the problems such as prolonged unhealing, foreign body reaction, lithogenesis, inflammatory reaction, erythema generation and induration in the current surgical suturing can be avoided; the collagen suture line is completely absorbed without absorption reaction and is not necessary to remove; the infection and the trouble caused by removing the line and the special pain caused by removing the line of a circumcision and the like can be avoided.

Description

[0001] Technical field: [0002] The invention relates to a method for preparing a suture, in particular to a method for preparing a collagen suture. [0003] Background technique: [0004] Medical sutures belong to the category of medical devices. Sutures are divided into two categories in the same industry: one is non-absorbable sutures: silk threads, polypropylene threads, nylon threads, etc.; the other is absorbable sutures: respectively for chemical and biological lines. At present, a large number of PGA chemically absorbable sutures are used in my country. According to the statistics of domestic sales in the industry last year, the sales of chemically absorbable sutures amounted to RMB 800 million, with an annual growth rate of about 4%. According to the information of Taiwan Institute of Chemical Industry, there are only three factories in the world that produce chemical line raw materials, which are extremely difficult to obtain and the cost increases a lot. In addit...

AI Technical Summary

Problems solved by technology

According to the information of Taiwan Institute of Chemical Industry, there are only three factories in the world that produce raw materials for chemical lines. It is extremely difficult to obtain and the cost increases a lot.

In addition, if the moisture content of the chemical thread is too high, the material will be hydrolyzed and deteriorated, the mechanical strength will be reduced, and the quality of the suture will be seriously affected.

Therefore, the raw materials of the chemical line rely heavily on imports, the procurement cycle is long, and the storage requirements are high