Application of codonopsis pilosula polysaccharides to preparation of functional food with effect of helping to inhibit prostate cancer

A technology for prostate cancer and Codonopsis polysaccharide, applied in the field of polysaccharides, can solve the problems of preparing polysaccharide components and the like, and achieve the effects of high purity and activity, stable and efficient process, and low cost

Active Publication Date: 2014-10-29
INFINITUS (CHINA) CO LTD
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no application of using Codonopsis pilosula as raw material to prepare polysaccharide components for the preparation of health food that can assist in the inhibition of prostate cancer

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of codonopsis pilosula polysaccharides to preparation of functional food with effect of helping to inhibit prostate cancer
  • Application of codonopsis pilosula polysaccharides to preparation of functional food with effect of helping to inhibit prostate cancer
  • Application of codonopsis pilosula polysaccharides to preparation of functional food with effect of helping to inhibit prostate cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The Codonopsis polysaccharide in this embodiment is prepared by the following method: get the raw material of Codonopsis pilosula, extract with boiling water, when extracting for the first time, the consumption of water is 20 times of the total mass of the raw material, and boil for 5 h; when extracting for the second time, water The amount of water is 20 times the total mass of raw materials, boiled for 3 h; the third extraction, the amount of water is 10 times the total mass of raw materials, boiled for 2 h to filter, combined filtrates, vacuum concentrated to about 1 / 10 of the original volume, The same below. The concentrated solution was treated with trichloroacetic acid to remove protein, and the same volume (the same below) of 30% trichloroacetic acid (mass percentage) was added. After the treatment time was 4 hours, it was neutralized with 10% NaOH (mass percentage), the same below, After neutralization, place the reaction solution in a dialysis bag and tie it fo...

Embodiment 2

[0032] Codonopsis pilosula polysaccharide in the present embodiment is prepared by the following method: get Codonopsis pilosula raw material, use boiling water to extract, when extracting for the first time, the consumption of water is 15 times of the total mass of Codonopsis pilosula raw material, boil 5 h; When extracting for the second time, The amount of water used was 15 times the total mass of Codonopsis pilosula raw materials, and boiled for 3 hours; for the third extraction, the amount of water used was 10 times the total mass of Codonopsis pilosula raw materials, boiled for 3 hours, filtered, combined filtrates, and concentrated in vacuo. The concentrated solution was treated with trichloroacetic acid to remove protein, and the same volume of 25% trichloroacetic acid (mass percentage) was added. After the treatment time was 3 h, it was neutralized with 10% NaOH (mass percentage). After neutralization, the reaction solution was placed in Dialyze in a dialysis bag, then...

Embodiment 3

[0034] Codonopsis pilosula polysaccharide in the present embodiment is prepared by the following method: take Codonopsis pilosula raw material, extract with boiling water, when extracting for the first time, the consumption of water is 10 times of the total mass of Codonopsis pilosula raw material, and boil for 3 h; when extracting for the second time, The amount of water used is 20 times the total mass of Codonopsis pilosula raw materials, and boiled for 3 h; for the third extraction, the amount of water used is 10 times the total mass of Codonopsis pilosula raw materials, boiled for 5 h and filtered, the filtrates are combined, concentrated in vacuum, and the concentrated solution is subjected to three extractions. Chloroacetic acid protein removal treatment, add the same volume of 15% trichloroacetic acid (mass percentage), after the treatment time is 5 hours, neutralize with 10% NaOH (mass percentage), after neutralization, put the reaction solution in a dialysis bag bag di...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses application of codonopsis pilosula polysaccharides to the preparation of a functional food with the effect of helping to inhibit prostate cancer. Optimally, the codonopsis pilosula polysaccharides are prepared from codonopsis pilosula and by the procedures of extracting with boiled water, removing proteins, carrying out dialysis and carrying out ethanol treatment. The codonopsis pilosula polysaccharides have the effect of adjusting a tumor microenvironment through a plurality of manners of inhibiting tumor angiogenesis, carrying out immune activation, inhibiting fibroblast growth of prostate cancer and the like, so that the codonopsis pilosula polysaccharides have the good effect of helping to inhibit prostate cancer.

Description

technical field [0001] The invention belongs to the technical field of polysaccharides, and in particular relates to the application of Codonopsis polysaccharides in the preparation of functional foods with the effect of assisting in inhibiting prostate cancer. Background technique [0002] The study of immune negative regulation provides a new strategy for tumor therapy. In the tumor microenvironment, there are a large number of negative regulatory cells, which interact and influence each other, accompanied by the co-evolution of tumor cells and the microenvironment. Due to the immunogenic changes and abnormal growth of tumor cells, fibroblasts are stimulated to release inflammatory factors, antigen-presenting cells transmit tumor antigen signals, and jointly recruit immune cells to infiltrate into the tumor, and the abnormal proliferation of tumor cells causes damage to adjacent cells. Compression, leading to ischemic necrosis and other tissue damage, produces a large num...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/09A61K31/715C08B37/00A61P35/00
CPCA23L29/30A23L33/00A23V2002/00A61K31/715C08B37/0003A23V2250/51
Inventor 马方励胡明华王培培梁明陈伟鸿
Owner INFINITUS (CHINA) CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap