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Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation

A traditional Chinese medicine preparation and technology for asthma are applied in the field of traditional Chinese medicine preparations for treating asthma and their preparation, and can solve problems such as large toxic and side effects

Inactive Publication Date: 2015-04-08
崔合芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, western medicines for treating asthma include: atropine, scopolamine, 654-2, ipratropium bromide, diltiazem, verapamil, nifedipine, etc., but most of them only target one or several symptoms of asthma , and the side effects of long-term use are relatively large, and the purpose of treating both symptoms and root causes cannot be achieved

Method used

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  • Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation
  • Traditional Chinese preparation used for treating asthma and preparation method of traditional Chinese preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] According to the actual production of Chinese medicine capsules by the Chinese medicine prescription of the present invention, the capsule numbering A, B are 2 optimal scheme proportioning preparations, the capsule numbering C, D are the minimum and maximum range proportioning preparations of the prescription, and every kind of capsule raw material is formulated Such as shown in Table 1.

[0037] Table 1 Raw material ratio of capsules (unit: kg)

[0038]

[0039] Weigh ephedra, asarum, tudinggui, goat milk fruit, pinellia, tangerine peel, tongguangsan, toad skin, poria cocos, yam, snow ginseng, astragalus, jujube, coltsfoot, vitex according to the traditional Chinese medicine prescription in Table 1 Chinese herbal medicines such as zizi, shilianzi, elm leaves, polygala, licorice, etc., were crushed and mixed, added 8 times the weight of purified water, decocted under reflux for 2 hours, and filtered; the filter residue was added with purified water 6 times the we...

Embodiment 2

[0040] Embodiment 2, the animal toxicity test of Chinese medicine capsule of the present invention

[0041](1) Test drug: the traditional Chinese medicine capsule prepared in Example 1 of the present invention, the capsule shell was broken, and the medicinal powder was prepared into a thin paste with purified water, and set aside.

[0042] Animals used in the test: normal grade NIH mice, weighing 21g±6g, half male and half female, all female mice were sterile; SD rats, initial weight 218±9g, half male and half female, all female rats were sterile.

[0043] (2) Acute toxicity test

[0044] The application of mice to carry out acute toxicity experiments shows that: the traditional Chinese medicine thin paste of the present invention is administrated into mice, and at a dose of 714.6g of crude drug / kg, after administration, the mice have a slight decrease in activity, and return to normal in about 1 hour, and continuous observation after administration After 7 days, none of the ...

Embodiment 3

[0048] The clinical effect test of embodiment 3 Chinese medicine capsules of the present invention

[0049] 1. Source and grouping of subjects

[0050] All the subjects were from the people's hospital of a certain city, who were admitted to asthma patients from May 2011 to October 2013, and 165 patients suitable for the test were screened out, including 100 males, aged 49-76 years, and 65 females For example, age 53-75 years. All subjects were equally divided into 5 groups, numbered as control group, group A, group B, group C and group D respectively.

[0051] 2. Experimental drugs

[0052] (1) Compound Methoxyphenamine Capsules, Zhunzi H20033669, Daiichi Sankyo Pharmaceutical Co., Ltd.;

[0053] (2) The capsules prepared in Example 1 of the present invention are numbered A, B, C, and D.

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Abstract

The invention discloses a traditional Chinese preparation used for treating asthma and a preparation method of the traditional Chinese preparation, and relates to the technical field of traditional Chinese medicine. The traditional Chinese preparation is composed of 19 types of traditional Chinese medicine including Chinese ephedra, asarum, evolvulus alsinoides, Elaeagnus conferta Roxb, pinellia ternate, tangerine peel, marsdenia tenacissima, toad skin, poria cocos, Chinese yam, Meconopsis racemosa Maxim, astragalus membranaceus, jujubes, tussilago farfara, negundo chastetree fruit, caesalpinia, siberian elm leaves, polygala tenuifolia and honey-fried licorice roots. The traditional Chinese preparation has a quite obvious curative effect on asthma, the preparation process is easy and convenient, and the preparation is high in stability, convenient to carry and take and easy to apply and popularize.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for treating asthma and a preparation method thereof. technical background [0002] Bronchial asthma (bronchial asthma, asthma) is a chronic airway inflammation involving a variety of cells, especially mast cells, eosinophils, and T lymphocytes. In susceptible individuals, this inflammation can cause recurrent wheezing and shortness of breath. Symptoms such as chest tightness and (or) cough usually occur at night and (or) in the early morning, but the symptoms can be relieved by themselves or after treatment. There are about 100 million asthma patients in the world. Asthma has become a major chronic disease that seriously threatens public health. The prevalence of asthma in my country is about 1%, and children can reach 3%. It is estimated that there are more than 10 million people with asthma in the country patie...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P11/06A61P7/06A61P25/20A61K35/65
CPCA61K35/65A61K36/076A61K36/17A61K36/185A61K36/268A61K36/27A61K36/28A61K36/39A61K36/481A61K36/484A61K36/66A61K36/69A61K36/725A61K36/752A61K36/85A61K36/8888A61K36/8945A61K36/898A61K2300/00
Inventor 崔合芳
Owner 崔合芳
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