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Methods and assessment scales for measuring wrinkle severity

A technology for evaluating scales and severity, applied in the field of grades, can solve the problem of wrinkles such as lack of wrinkle measurement equipment

Inactive Publication Date: 2015-04-22
REVANCE THERAPEUTICS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Previous wrinkle treatments lacked reliable wrinkle measurement equipment to assess wrinkle severity

Method used

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  • Methods and assessment scales for measuring wrinkle severity
  • Methods and assessment scales for measuring wrinkle severity
  • Methods and assessment scales for measuring wrinkle severity

Examples

Experimental program
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Effect test

Embodiment 1

[0044] Lateral Canthus Line Evaluation Scale

[0045] This example describes a clinical scale, called "Investigator's Global Assessment of Lateral Canthal Line Severity Scale" ("IGA-LCL scale"), which was developed using to evaluate the lateral canthal line in a relaxed calm facial position. The IGA-LCL scale allows direct assessment of the effects of chemodenervation drugs on the relevant target muscle, the orbicularis muscle and thus provides an appropriate and specific means of assessing drugs.

[0046] The IGA-LCL scale was developed to be content valid, reliable, construct valid, able to detect clinical changes and to be able to establish thresholds for treatment benefit. The IGA-LCL scale was refined and validated in several steps. First, conduct conceptual inspiration and establish content validity. The identification of important and relevant wrinkle physical features for assessing the lateral canthal line was based on a literature review, clinician input, and patie...

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Abstract

This invention provides devices, methods, and assessment scales for assessing the severity of wrinkles. Wrinkle assessment using the devices, methods, and assessment scales of the invention can be performed in a clinical setting for the purpose of simply characterizing a wrinkle, or as part of a treatment regimen that varies according to the severity of the wrinkle. Thus, this invention also provides methods of reducing the appearance of wrinkles, and kits comprising for evaluating and treating wrinkles.

Description

technical field [0001] The present invention relates to methods and assessment scales for assessing wrinkle severity levels. Background technique [0002] Wrinkles are a well-known phenomenon of aging. Depending on the level of wrinkle severity, treatments that reduce the different signs of wrinkle have different effects. [0003] Aging-related wrinkle development has been previously described by Glogau in "Aesthetic and anatomic analysis of the aging skin" Semin. Cutan. Med. Surg. 1996;15(3):134-138 , and categorized into successive stages of development. For example, in teenage subjects, lateral canthal lines (LCL) that emanate from the distal corners of the eyes and are known as crow's feet occur naturally when smiling but are absent when relaxed. Such a lateral canthal line reflects positive emotional connection, but is not considered a sign of aging. Patients usually only seek treatment after they also have lateral canthal lines when their facial muscles are relaxed...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/107
CPCA61B5/4839A61B5/442A61B5/1072A61P17/00
Inventor J·M·沃A·布里泽
Owner REVANCE THERAPEUTICS INC
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