Traditional Chinese medicine preparation for preventing ventricular remodeling of myocardial infarction

Abstract

The invention discloses a traditional Chinese medicine preparation for preventing ventricular remodeling of myocardial infarction. The traditional Chinese medicine preparations, namely longan pulp, downy aletris, king pedicularis root, lousewort root, asiatic bilberry root, dockleaved knotweed herb root, scarlet kadsura root, root of Yunnan camptandra, hibiscus root and smallflower milkwort herb with root are selected to be decocted into a decoction. The traditional Chinese medicine preparation is capable of preventing ventricular remodeling of myocardial infarction, strengthening the middle warmer, dredging collaterals, combining dredging with tonifying, tonifying qi to nourish blood, tonifying qi to generate vigorous commander of blood, smoothening blood supply and dispersing blood stasis to complement each other, so that a relatively good clinical effect is obtained.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine preparation for preventing ventricular remodeling after myocardial infarction. Background technique [0002] Ventricular remodeling after myocardial infarction mainly refers to the pathological changes in the size, shape, tissue structure and myocardial function of ventricular myocardium after myocardial infarction due to the extensive ischemia and hypoxia damage of myocardial cells and the increase in the remaining myocardial load. Atrial natriuretic peptide and TNF-α play an important role in the formation of ventricular remodeling. Among them, atrial natriuretic sodium mainly directly inhibits the sodium ion transport in the proximal convoluted tubule and intramedullary collecting duct of the kidney and inhibits the secretion and activity of adrenaline, thereby reducing the preload and afterload of the heart, increasing the oxygen sup...

AI Technical Summary

Problems solved by technology

Among them, atrial natriuretic sodium mainly directly inhibits the sodium ion transport in the proximal convoluted tubule and intramedullary collecting duct of the kidney, and inhibits the secretion and activity of adrenaline, thereby reducing the cardiac preload and postload, increasing the oxygen supply of myocardial cells, reducing oxygen consumption, and slowing down the myocardial cells. Hypertrophy, especially in the centrifugal process, reducing heart enlargement, and preserving the remaining myocardial function of the patient's heart. Previous studies have suggested that myocardial ischemia leads to myocardial necrosis and physical, chemical, and biological damage to the myocardium will cause ventricular myocytes to synthesize, secrete And the release of atrial natriuretic peptide abnormalities, general pathological conditions such as ventricular hypertrophy and cardiac function decline in vivo atrial natriuretic peptide secretion decreased significantly; in addition, TNF-α can lead to normal cardiomyocyte apoptosis after acting on cardiomyocytes, thereby It leads to a decrease in the number of cardiomyocytes, and it will also cause an increase in the collagen content in the myocardium, leading to the occurrence of ventricular remodeling