Novel compound anti-hypertensive drug

Abstract

The invention discloses a compound preparation used for treating hypertension, particularly a novel compound anti-hypertensive drug which comprises 5-20 mg of nitrendipine and 5-50 mg of metoprolol. The novel compound anti-hypertensive drug solves the problem that when nitrendipine and metoprololare are clinically used at present, side effects are obviously increased to guarantee the curative effect by increase of drug dose since only one of nitrendipine and metoprololare is put into use. According to the novel compound preparation, nitrendipine and metoprololare are used together to achieve synergetic and complementary curative effects; and the novel compound anti-hypertensive drug increases the tolerance of patients, improves the compliance, is reduced in dose to relieve adverse reaction, and is convenient to take and low in price.

Description

technical field [0001] The invention relates to the technical field of medicine and discloses a new compound antihypertensive drug. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Commonly used drugs for the treatment of hypertension include the calcium antagonist nitrendipine and the beta-blocker metoprolol. [0004] Nitrendipine (Nitrendipine), the chemical name is 2,6-dimet...

AI Technical Summary

Problems solved by technology

[0014] The product of the present invention overcomes that when nitrendipine and metoprolol are used clinically, the drug dose is increased to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; , and the use of inaccurate clinical dosages affects the defects of drug efficacy

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