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The application of the flavonoids of thalassemia in the preparation of anti-hypoxic drugs

An anti-hypoxic drug, the technology of the flavonoids of thalassemia, which is applied in the field of medicine and can solve the problems of narrow application range and other problems

Active Publication Date: 2019-03-19
中国人民解放军联勤保障部队第九四〇医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are very few studies on the biopharmaceutical activity of thalassemia flavonoids, and the compound has only been isolated from six plants of Andrographis paniculata, Suzhou chrysanthemum, chrysanthemum chinensis, Maojiancao, rhubarb and Artemisia sinica, and its application range is very narrow

Method used

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  • The application of the flavonoids of thalassemia in the preparation of anti-hypoxic drugs
  • The application of the flavonoids of thalassemia in the preparation of anti-hypoxic drugs
  • The application of the flavonoids of thalassemia in the preparation of anti-hypoxic drugs

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Experimental program
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Effect test

Embodiment 1

[0052] The ingredients and content of the flavonoids for injection are as follows:

[0053]

[0054] Prepared according to the routine operation of injections, a total of 1000 injections of 2ml were made, each containing 10mg of flavonoids of apricot.

Embodiment 2

[0056] The composition and content of the chrysanthemum flavonoids for injection (freeze-dried) are:

[0057]

[0058] Prepared according to the conventional operation of freeze-dried powder injection, a total of 1000 injections of 2ml were prepared, each containing 10mg of flavonoids.

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PUM

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Abstract

The present invention discloses new application of moslosooflavone in preparation of anti hypoxic drugs, a whole animal hypoxic experiment shows that the moslosooflavone has significant anti-hypoxic activity, not only can extend the survival time of atmospheric pressure closed hypoxic mice, but can also extend the survival time of acute decompression hypoxic mice, and the functional mechanism may be associated with remission of hypoxia-induced energy deficiency and metabolic disorders, protecting of functions of ATPase on cell membrane and improvement of the antioxidant capacity.

Description

technical field [0001] The present invention relates to the application method of the flavonoids of arborescens and belongs to the field of medicine. Background technique [0002] The research on the prevention and treatment of acute mountain sickness is a major problem in today's medical field, and there are very few effective anti-altitude hypoxia drugs in the world. Thalasso flavone is also called Moslosooflavone, and its chemical name is 5-hydroxy-7,8-dimethoxyflavone. At present, there are very few studies on the biopharmacological activity of thalassemia flavonoids. The compound has only been isolated from six plants: Andrographis paniculata, Suzhou chrysanthemum, chrysanthemum chinensis, Maojiancao, rhubarb and Artemisia sinica, and its application range is very narrow. Contents of the invention [0003] The technical problem to be solved by the present invention is to overcome the existing defects and provide a new application of the thalassemia flavonoids—the app...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61P39/00A61P9/10
Inventor 景临林马慧萍樊鹏程何蕾高荣敏贾正平
Owner 中国人民解放军联勤保障部队第九四〇医院
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