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Composition with blood-fat-reducing effect and preparation method of composition

A technology for lowering blood lipids and compositions, which can be applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, and can solve problems such as rhabdomyolysis

Inactive Publication Date: 2015-12-23
FOSHAN LANGDA INFORMATION TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of hyperlipidemia is mainly based on statins, but statins are likely to cause side effects such as myalgia, myopathy, and rhabdomyolysis, and it is necessary to focus on monitoring blood lipids and safety indicators

Method used

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  • Composition with blood-fat-reducing effect and preparation method of composition
  • Composition with blood-fat-reducing effect and preparation method of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Composition: Albizia Julibrissin 20kg, Comfrey 32kg, Woody Fragrance 16kg, Wulingzhi 8kg, Millipede Spatholobus 10kg.

[0023] (1) Extraction: Take by weighing 20kg of Albizia Julibrissin, Comfrey 32kg, Woody Fragrance 16kg, and Caulis Spatholobus 10kg in proportion to the above mass parts, mix evenly, pulverize into coarse powder, put into a multifunctional extraction tank, and extract 3 times; Add 8 times the amount of water for the first time and extract for 2 hours; add 6 times the amount of water for the second time and extract for 1 hour; add 1 times the amount of water for the third time and extract for 1 hour; (2) Alcohol precipitation: put the concentrated solution 1 in the alcohol precipitation tank, turn on the stirring device and stir for 10 minutes, add 4 times of 75% ethanol under stirring state, stop adding ethanol. Continue to stir for 20 minutes; stop stirring, let stand for 5 hours, pump the supernatant, recover ethanol, and obtain concentrated soluti...

Embodiment 2

[0025] Composition: Albizia Julibrissin 50kg, Comfrey 45kg, Woody Fragrance 25kg, Wulingzhi 15kg, Millipede Spatholobus 20kg.

[0026] (1) Extraction: take by weight 50kg of Albizia juliensis bark, 45kg of comfrey, 25kg of woody incense, and 20kg of Caulis Spatholobus in proportion to the above mass parts, mix evenly, pulverize into coarse powder, put into a multifunctional extraction tank, and extract 3 times; Add 10 times the amount of water for the first time and extract for 4 hours; add 8 times the amount of water for the second time and extract for 3 hours; add 3 times the amount of water for the third time and extract for 2 hours; combine the three extracts and pass 80 (2) alcohol precipitation: put the concentrated liquid 1 in the alcohol precipitation tank, turn on the stirring device and stir for 20 minutes, add 5 times of 95% ethanol under stirring state, stop adding ethanol. Continue to stir for 30 min; stop stirring, and after standing still for 10 h, pump the sup...

Embodiment 3

[0028]Composition: Albizia Julibrissin 30kg, Comfrey 35kg, Woody Fragrance 18kg, Wuling Zhi 8kg, Millipeda 10kg. (1) Extraction: Take by weighing 30kg of Albizia Julibrissin, 35kg of Comfrey 35kg, 18kg of woody incense, and 10kg of Mildew Spatholobus in proportion to the above mass parts, mix evenly, pulverize into coarse powder, put into a multifunctional extraction tank, and extract 3 times; Add 9 times the amount of water for the first time and extract for 3 hours; add 7 times the amount of water for the second time and extract for 2 hours; add 2 times the amount of water for the third time and extract for 2 hours; (2) Alcohol precipitation: put the concentrated liquid 1 in the alcohol precipitation tank, turn on the stirring device and stir for 15 minutes, add 4.5 times of 80% ethanol under stirring state, stop adding ethanol. Continue to stir for 25 minutes; stop stirring, and after standing still for 8 hours, pump the supernatant, recover ethanol, and obtain concentrate...

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Abstract

The invention discloses a composition with a blood-fat-reducing effect and a preparation method of the composition. The composition is prepared from the following raw materials in parts by weight: 20-50 parts of cortex albiziae, 32-45 parts of lithospermum, 16-25 parts of elecampane, 8-15 parts of trogopterus dung, and 10-20 parts of caulis spatholobi. The raw materials are subjected to water-decocting extraction, alcohol extraction, water precipitation and concentration to prepare extract, thus preparing the medicine composition with the blood-fat-reducing effect. The medicine composition has the effects of invigorating the circulation of blood, reducing swelling, clearing and activating the channels and collaterals, promoting qi circulation to relieve pain, and reducing blood fat, and is used for the treatment and prevention and treatment of the hyperlipidemia.

Description

technical field [0001] The invention relates to a composition with hypolipidemic effect and a preparation method, belonging to the technical field of medicine and health care. Background technique [0002] In recent years, with the improvement of people's living standards, people's intake of protein and fat in food has continued to increase. The phenomenon of high blood lipids is more common among middle-aged and elderly people and urban white-collar workers, and it has also shown a younger age in recent years. The main reasons may be: on the one hand, the improvement of the quality of life, the increase in fat intake, and the unhealthy eating habits lead to changes in the blood lipid composition in the human body; on the other hand, the high pressure of life and work, and abnormal work and rest habits , leading to the decline of young people's physical fitness and self-regulation ability, especially young people who do not eat breakfast and are unevenly hungry and full are ...

Claims

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Application Information

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IPC IPC(8): A61K36/486A61P3/06A61K35/24
Inventor 李鸿雁
Owner FOSHAN LANGDA INFORMATION TECH
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