Autism serum polypeptide marker SERPINA5-A and application thereof
A technology for serum peptides and autism, applied in biological testing, material inspection products, measuring devices, etc., can solve problems such as the lack of quantifiable indicators
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[0021] The autism serum polypeptide molecule provided by the invention is a newly screened autism serum diagnostic marker, its expression has specificity, and can be applied to autism diagnosis. The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.
[0022] The specific screening of the serum diagnostic markers for autism is as follows:
[0023] First, the liquid protein chip technology was used to separate and extract the serum protein peptides of children with autism and normal controls, and MALDI-TOF-MS was used to capture the protein and peptide profiles of children with autism and normal controls, and the software ClinProTools2.1 was used to compare and analyze the protein peptides of children with autism. The differences in the serum protein and polypeptide spectra of children and normal people were used to find out the scores of protein polypeptid...
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