Controlled release delivery system for nasal application of neurotransmitters

a delivery system and neurotransmitter technology, applied in the field of controlled release delivery system for nasal application of neurotransmitters, can solve the problems of little knowledge on factors controlling the nasal delivery of drugs to the brain, parkinson's disease, and unsuitable administration mode of dopamine for neurological disorders, and achieve the effect of increasing the bioavailability of drugs and effective sustained serum levels
US20090227550A1Inactive Publication Date: 2009-09-10MATTERN PHARMA
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Patent Information

Authority / Receiving Office
US Ā· United States
Patent Type
Applications(United States)
Current Assignee / Owner
MATTERN PHARMA
Publication Date
2009-09-10
Estimated Expiration
Not applicable Ā· inactive patent

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Abstract

This invention relates to a galenical gel formulation for nasal administration of neurotransmitters / neuromodulators such as dopamine, serotonin or pregnenolone and progesterone. The special lipophilic or partly lipophilic system of the invention leads to high bioavailability of the active ingredient in plasma and brain caused by sustained serum levels and / or direct or partly direct transport from nose to the brain.
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Description

INCORPORATION BY REFERENCE

[0001] This application is a continuation-in-part application of International Patent Application Serial No. PCT / EP2007 / 008409 filed 27 Sep. 2007, which published as PCT Publication No. WO / 2008 / 040488 on 10 Apr. 2008, which claims benefit of U.S. Provisional Application No. 60 / 828,109 filed 4 Oct. 2006.

[0002] The foregoing application, and all documents cited therein or during their prosecution (ā€œappln cited documentsā€) and all documents cited or referenced in the appln cited documents, and all documents cited or referenced herein (ā€œherein cited documentsā€), and all documents cited or referenced in herein cited documents, together with any manufacturer's instructions, descriptions, product specifications, and product sheets for any products mentioned herein or in any document incorporated by reference herein, are hereby incorporated herein by reference, and may be employed in the practice of the invention.FIELD OF THE INVENTION

[0003] The invention generally re...

Claims

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