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Drug for relieving reaction after tumor radiotherapy and preparation method of drug

A tumor radiotherapy and reaction technology, applied in the direction of anti-tumor drugs, drug combinations, pharmaceutical formulas, etc., can solve the problems of large side effects, etc., achieve the effect of convenient administration, promotion of standardized treatment, and good patient tolerance

Inactive Publication Date: 2016-07-27
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine generally treats symptoms, or takes some painkillers and antibiotics for treatment. There is no specific drug, and the side effects are large, and there is a certain degree of drug dependence.

Method used

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  • Drug for relieving reaction after tumor radiotherapy and preparation method of drug

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation of the medicament for alleviating tumor response after radiotherapy of the present invention comprises the following steps:

[0018] Weigh 22 parts of Polygonatum, 22 parts of Rehmannia, 13 parts of Caterpillar, 10 parts of Radish, 22 parts of Codonopsis, 6 parts of Prunella vulgaris, 6 parts of Gorgon, 4 parts of Huanglongteng, 4 parts of Morinda officinalis, Alisma 4 parts, 12 parts of Angelica, 9 parts of Tianma, 6 parts of Nepeta, 6 parts of Cangzhu, 9 parts of Gentiana, 3 parts of Kochia, 3 parts of Fangfeng, 3 parts of Tangerine Peel, crushed into powder, add water to decoct, after boiling Simmer for 3 hours, let stand to settle for 10-12 hours, filter, filter the residue for later use, concentrate the filtrate to obtain a clear paste, dry the obtained clear paste at a temperature of 40°C-55°C by microwave under reduced pressure to obtain a dry extract block A, Crush the drug to obtain the drug for alleviating the reaction of the tumor after radiot...

Embodiment 2

[0020] The preparation of the medicament for alleviating tumor response after radiotherapy of the present invention comprises the following steps:

[0021] a. Weigh 22 parts of Rhizoma Polygonatum, 22 parts of Rehmannia, 13 parts of Caterpillar, 10 parts of Radish, 22 parts of Codonopsis, 6 parts of Prunella vulgaris, 6 parts of Gorgon, 4 parts of Huanglongteng, 4 parts of Morinda officinalis, Alisma 4 parts, Angelica 12 parts, Gastrodia elata 9 parts, Nepeta 6 parts, Atractylodes 6 parts, Gentiana 9 parts, Fangfeng 3 parts, tangerine peel 3 parts, crushed into powder, add water to boil, then simmer for 3 hours , set aside to settle for 10-12 hours, filter, filter residue for later use, concentrate the filtrate to obtain a clear paste, and dry the obtained clear paste at a temperature of 40°C-55°C by microwave under reduced pressure to obtain dry extract pieces.

[0022] b. Weigh 3 parts of Kochia scoparia by weight, stir-fry over low heat until the skin is browned, take it ou...

Embodiment 3

[0025] The preparation of the medicament for alleviating tumor response after radiotherapy of the present invention comprises the following steps:

[0026] a. Weigh 20 parts of sealwort, 20 parts of raw land, 12 parts of scorpion, 9 parts of radish, 20 parts of codonopsis, 5 parts of Prunella vulgaris by weight, grind them into powder, add water to decoct, boil with low heat for 3 hours, let stand to settle for 10-12 hours, filter, filter residue for later use, concentrate the filtrate to obtain a clear paste, and dry the obtained clear paste at a temperature of 40°C-55°C by microwave under reduced pressure to obtain a dry extract block A;

[0027] b. Weigh 5 parts of Gorgon, 3 parts of Huanglongteng, 3 parts of Morinda officinalis, 3 parts of Alisma, 105 parts of Angelica, and 8 parts of Gastrodia elata by weight, grind them into powder, and add 10 times the weight of raw materials with a concentration of 70% Ethanol, soaked for 3 hours, ultrasonically extracted with an ultra...

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Abstract

The invention relates to a drug for relieving a reaction after tumor radiotherapy. The drug is prepared from manyflower solomonseal rhizomes, radix rehmanniae, caulis trachelospermi, semen raphani, radix codonopsis, spica prunellae, semen euryales, rattan stems and roots of schisandra propinqua(Wall.)Hook.f.et Thoms.var.intermedia A.C.Smith, radix morindae officinalis, rhizoma alismatis, radix angelicae sinensis, rhizoma gastrodiae, herba schizonepetae, rhizoma atractylodis, radix gentianae macrophyllae, fructus kochiae, radix saposhnikoviae and pericarpium citri reticulatae. The traditional Chinese medicine compound for relieving an adverse radiotherapy reaction adopts scientific proportioning, all ingredients can be mutually coordinated and promoted, and the synergic effect is achieved. The drug is convenient to take, the tolerance of a patient is good, an adverse effect is not found after the patient takes the drug for a long time, and after a normative Chinese patent medicine preparation is obtained, normalized treatment through traditional Chinese medicine can be promoted.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for alleviating radiotherapy side effects and a preparation method thereof. Background technique [0002] Radiation therapy is one of the most commonly used treatments for malignant tumors, and clinically most tumor patients will receive radiation therapy. Radiation therapy is radiation therapy, which refers to the use of radiation to kill malignant cells in the body, so as to achieve the purpose of treating malignant tumors. Radiation therapy is a physical therapy for tumors. It has become an important means of treating malignant tumors and can produce good results for many cancers. Radiotherapy can quickly act on the local area or the whole body, and the short-term treatment effect is better, but the side effects of radiotherapy are also very large. While killing tumor cells, they also kill...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P35/00A61P39/00A61P1/08A61P25/00A61P29/00A61P1/14A61P37/04
CPCA61K36/8988A61K36/232A61K36/238A61K36/24A61K36/284A61K36/31A61K36/344A61K36/51A61K36/536A61K36/538A61K36/57A61K36/62A61K36/70A61K36/746A61K36/752A61K36/804A61K36/884A61K36/8969A61K2236/331A61K2236/333A61K2236/51A61K2300/00
Inventor 肖文静刘希光张碧媛
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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