Eye fundus image vessel segmentation method based on local enhancement active contour module

An active contour model and fundus image technology, which is applied in image analysis, image data processing, instruments, etc., can solve the problems of uneven gray scale fundus image segmentation, difficulty in vascular network segmentation, and low contrast of vascular edges.

Inactive Publication Date: 2016-10-05
SHENYANG INST OF AUTOMATION - CHINESE ACAD OF SCI
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Problems solved by technology

However, the active contour model usually used for fundus blood vessel segmentation in medical images only uses the global grayscale features of the image, and has a good segmentation result for uniform grayscale fundus images, but it is difficult to achieve accurate segmentation for uneven grayscale fundus images.
[0004] Affected by factors such as the complex shape of blood vessels, low contrast of blood vessel edges, and image noise in medical fundus images, there is currently no general blood vessel segmentation algorithm that can be applied to all medical fundus images.
Moreover, for fundus images with lesions, the segmentation of the vascular network is more difficult due to the interference of the lesion area (such as hemorrhage, macula, etc.)

Method used

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  • Eye fundus image vessel segmentation method based on local enhancement active contour module
  • Eye fundus image vessel segmentation method based on local enhancement active contour module
  • Eye fundus image vessel segmentation method based on local enhancement active contour module

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Embodiment Construction

[0048] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0049] The present invention utilizes the locally enhanced active contour model to accurately segment the fundus blood vessels, and combines the global energy to correctly guide the segmentation results. The innovation includes two aspects: a Gaussian kernel function is used to extract the local information of the image to construct a local energy functional to ensure that the segmentation model can accurately segment the target in the image with uneven gray scale. The Gaussian kernel function has the property of regional scaling, that is, the The range of local information is controlled by kernel function parameters; according to the gray distribution characteristics of blood vessels in medical fundus images, the corresponding global energy functional term is introduced to make the curve evolution process more stable and faster.

[0050] Such...

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Abstract

The invention relates to an eye fundus image vessel segmentation method based on a local enhancement active contour module. The method comprises: according to a feature vector of a Hessian matrix, vessel enhancement in an eye fundus image is carried out; curvature distribution statistics is carried out on the enhanced image to obtain an eyeball edge and get rid of the eyeball edge; and with a local enhancement active contour module, enhanced image segmentation is carried out by combining global energy information, thereby extracting an eye fundus vessel. According to the invention, on the basis of gray level distribution characteristics of the vessel in the medical eye fundus image, a local energy function is established and a global energy functional item is combined, so that the curve evolution process becomes stable; the speed is accelerated; and the vessel in the eye fundus image can be extracted precisely and effectively.

Description

technical field [0001] The invention relates to a blood vessel segmentation method of a fundus image, in particular to a blood vessel segmentation method of a fundus image based on a local enhanced active contour model. It is mainly used in the fields of medical images, computer vision and digital image processing technology. Background technique [0002] The morphological and structural characteristics of the retinal vascular network directly reflect the health of the fundus, as well as the course, severity, and prognosis of cardiovascular and cerebrovascular diseases such as diabetes and arteriosclerosis. Therefore, the results of blood vessel segmentation in fundus images directly affect the accuracy of fundus detection, and also affect the results of other subsequent processing and analysis. [0003] At present, researchers have proposed a large number of different algorithms, although most of these algorithms have achieved certain success in varying degrees, but there ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00
Inventor 范慧杰丛杨唐延东
Owner SHENYANG INST OF AUTOMATION - CHINESE ACAD OF SCI
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