Drug composition for treating Aids and preparation method of drug composition

A composition, a technology for AIDS dementia, applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of increasing T lymphocytes, increasing the number of B lymphocytes in young mice, etc.

Inactive Publication Date: 2017-05-24
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Giving LACA mice 12.5g (crude drug) / kg of mulberry water decoction every day for 10 consecutive days can significantly increase the T lymphocytes of mice in different age groups; but the same dose of mulberry water decoction can only increase The number of B lymphocytes in young mice has no significant effect on aged mice over 1 year old

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: The pharmaceutical composition and preparation method thereof for the treatment of AIDS dementia syndrome psychobehavioral symptoms

[0037] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating the mental behavioral symptoms of AIDS dementia syndrome are: 2410 parts by weight of mulberry fruit, 2190 parts by weight of saffron, 1880 parts by weight of Shandayan, 930 parts by weight of Polygonatum, and 4200 parts by weight of Spirogyra parts, 101 parts by weight of cysteine, 72 parts by weight of dioleoyl lecithin;

[0038] Preparation:

[0039] (1) Take mulberry fruit, saffron, Shan Dayan, sealwort, Spirogyra, cysteine, and dioleoyl lecithin according to the ratio of raw materials, mix them evenly, and use ethanol with a concentration of 36% by weight as a solvent. ℃ warm immersion extraction, the number of extractions is 9 times, each extraction time is 24 hours, and the amount of solvent used each time is 4...

Embodiment 2

[0042] Embodiment 2: the pharmaceutical composition and preparation method thereof for the treatment of AIDS dementia syndrome psychobehavioral symptoms

[0043] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating the mental and behavioral symptoms of AIDS dementia syndrome are: 2360 parts by weight of mulberry fruit, 2240 parts by weight of saffron, 1830 parts by weight of Shandayan, 990 parts by weight of Polygonatum, and 4150 parts by weight of Spirogyra 106 parts by weight of cysteine, 67 parts by weight of dioleoyl lecithin;

[0044] Preparation:

[0045] (1) Take mulberry fruit, saffron, Shan Dayan, sealwort, Spirogyra, cysteine, and dioleoyl lecithin according to the ratio of raw materials, mix them evenly, and use ethanol with a concentration of 36% by weight as a solvent. ℃ warm immersion extraction, the number of extractions is 9 times, each extraction time is 24 hours, and the amount of solvent used each time is 44 t...

Embodiment 3

[0048] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of AIDS dementia syndrome psychobehavioral symptoms

[0049] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating the mental behavioral symptoms of AIDS dementia syndrome are: 2460 parts by weight of mulberry fruit, 2140 parts by weight of saffron, 1930 parts by weight of Shandayan, 890 parts by weight of Polygonatum, and 4250 parts by weight of Spirogyra parts, 96 parts by weight of cysteine, 77 parts by weight of dioleoyl lecithin;

[0050] Preparation:

[0051] (1) Take mulberry fruit, saffron, Shan Dayan, sealwort, Spirogyra, cysteine, and dioleoyl lecithin according to the ratio of raw materials, mix them evenly, and use ethanol with a concentration of 36% by weight as a solvent. ℃ warm immersion extraction, the number of extractions is 9 times, each extraction time is 24 hours, and the amount of solvent used each time is 44...

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Abstract

The invention discloses a drug composition for Aids dementia complex neuropsychiatric symptoms and a preparation method of the drug composition. The drug composition is prepared from Fructus Mori Albae, Stigma Croci, red psychotria leaves, Manyflower Solomonseal Rhizome, Spirogyra, aminothiopropionic acid and Dioleoyl Phosphatidylcholine in proportion. The drug composition can be prepared into various drug forms according to a conventional preparation technology. The effect on treating the Aids dementia complex neuropsychiatric symptoms is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating mental and behavioral symptoms of AIDS dementia syndrome and a preparation method thereof. Background technique [0002] The epidemic situation of AIDS in my country can be summarized as follows: the number of reported HIV-infected persons in the country has exceeded 40,000, and the estimated number of infected persons has exceeded 1 million. Contact transmission, blood transmission and mother-to-child transmission) all exist. The national AIDS epidemic has passed through the dissemination period and the local epidemic period and has turned into a widespread epidemic period. [0003] At this stage, my country is still in a period of low AIDS prevalence, but the AIDS epidemic has a growing trend. In recent years, the number of patients has increased significantly, facing the peak of AIDS incidence and dea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P25/28A61P31/18A61K31/198A61K31/685
CPCA61K31/198A61K31/685A61K36/05A61K36/74A61K36/88A61K36/8969A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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