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37 results about "Dioleoyl phosphatidylcholine" patented technology
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1,2-dioleoyl-sn-glycero-3-phosphocholine (1+) is a 1,2-diacyl-sn-glycero-3-phosphocholine in which the phosphatidyl acyl groups are both oleoyl. It is a conjugate acid of a 1,2-dioleoyl-sn-glycero-3-phosphocholine.
Refining method of dioleoyl phosphatidylcholine
PendingCN121574151AGroup 5/15 element organic compoundsPhosphatide foodstuff compositionsPtru catalystPhysical chemistry
The invention provides a refining method of dioleoyl phosphatidylcholine, which comprises the steps of synthesis, adsorption, deep eutectic solvent extraction, recrystallization, drying and the like, by reasonably designing a multi-stage purification process, adsorption treatment, deep eutectic solvent (DES) selective extraction and recrystallization process are organically combined, and the purity of the dioleoyl phosphatidylcholine is greatly improved. According to the present invention, the unreacted fatty acid, the condensation catalyst and the by-product thereof, and other polar impurities are efficiently removed, the purity of the DOPC product refined through the method can stably achieve more than 99.5%, the physical and chemical properties are excellent, the batch-to-batch difference is small, and the consistency and the stability of the product are significantly improved.
Owner:HUBEI GEDIAN HUMANWELL PHARMA EXCIPENTS