Light-shielding type medical PVC (Polyvinyl Chloride) infusion tube composition and preparation method of light-shielding type medical PVC infusion tube composition

Abstract

The invention provides a light-shielding type medical PVC (Polyvinyl Chloride) infusion tube composition and a preparation method of the light-shielding type medical PVC infusion tube composition and belongs to the technical field of PVC infusion tube compositions. The light-shielding type medical PVC infusion tube composition is prepared from the following raw materials in parts by weight: 100 parts of polyvinyl chloride resin, 1.0 to 3.0 parts of a thermal stabilizer, 40 to 60 parts of a plasticizer, 1.5 to 4 parts of a compound light stabilizer, 0.01 to 0.025 part of titanium dioxide and 0.1 to 0.2 part of a lubricant; the compound light stabilizer is prepared by mixing a hindered amine light stabilizer, phenyl salicytate, benzotriazoles and 4-(1-naphthylazo)-1-naphthol. The light-shielding type medical PVC infusion tube composition provided by the invention has the advantages of less light capable of penetrating through a waveband of 290nm to 450nm, high transparency and no toxin.

Description

technical field [0001] The invention belongs to the technical field of PVC transfusion tube composition, and in particular relates to a light-shielding medical PVC transfusion tube composition and a preparation method thereof. Background technique [0002] In the clinical infusion process, some drugs (such as the anti-tuberculosis drug PAS) are easy to decompose when exposed to light, resulting in a decrease in curative effect, so they need to be infused in a light-proof environment. When light drugs are infused, dark plastic containers are often temporarily used to wrap the infusion bottle and the infusion tube. However, there are still many shortcomings and deficiencies in this operation method, which is not conducive to observing the liquid level and is inconvenient to operate. The wavelength range of the light that is likely to cause drug decomposition is 290-450nm. The national standard requires that the light-proof infusion tube has a transmittance of 290-450nm band li...

AI Technical Summary

Problems solved by technology

[0003] The applicant found in the research that: the existing infusion tube composition has the problem of narrow light-shielding band, which easily leads to changes in the drug properties of the infusion bag or infusion tube when storing light-proof drugs

In the prior art, due to the use of a large amount of opacifying agents, the composition with a wider light-shielding band has the problem of poor light transmission, which leads to inconvenience in observation during use.

However, when applied to infusion materials, the added light stabilizer often has the problem of precipitation and contamination of the liquid medicine, which poses a safety hazard to the health of patients.