Drug composition for treating synovitis

A composition and a technology for synovitis, which are applied in the field of pharmaceutical compositions for the treatment of synovitis and their preparation, and can solve the problems of many adverse reactions, easy recurrence of disease, and difficult to cure.

Inactive Publication Date: 2017-05-31
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the conservative treatment for knee osteoarthritis mostly uses non-steroidal anti-inflammatory drugs, hormones, etc., but these methods have many

Method used

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  • Drug composition for treating synovitis

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Effect test

Embodiment 1

[0034] Embodiment 1: the pharmaceutical composition for the treatment of synovitis and preparation method thereof

[0035] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating synovitis are: 140g of Erxiancao, 90g of Euonymus euonymus 90g, 25g of Saponin II, 70g of Black Heart Fern, and 50g of Zaiguo;

[0036] Preparation:

[0037] (1) According to the proportion of raw materials, take Xiaoerxiancao, Euonymus daguna, Saponin II of Burnet elm, Fern fern, and Zaiguo, mix them evenly, use ethanol with a concentration of 33% by weight as a solvent, and extract by warm soaking at 37.5°C. The number of extractions is 16 times, each extraction time is 35 hours, and the amount of solvent used each time is 60 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, and concentrates to a relative density of 1.12 , filtered, the medicinal solution passes through the ...

Embodiment 2

[0040] Embodiment 2: the pharmaceutical composition for the treatment of synovitis and preparation method thereof

[0041] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating synovitis are: 160g of Erxiancao, 80g of Euonymus euonymus 30g, 30g of Burnet saponin II, 60g of Black Heart Fern, and 70g of Zaiguo;

[0042] Preparation:

[0043] (1) According to the proportion of raw materials, take Xiaoerxiancao, Euonymus daguna, Saponin II of Burnet elm, Fern fern, and Zaiguo, mix them evenly, use ethanol with a concentration of 33% by weight as a solvent, and extract by warm soaking at 37.5°C. The number of extractions is 16 times, each extraction time is 35 hours, and the amount of solvent used each time is 60 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, and concentrates to a relative density of 1.12 , filtered, the medicinal solution passes th...

Embodiment 3

[0046] Embodiment 3: the pharmaceutical composition for the treatment of synovitis and preparation method thereof

[0047] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating synovitis are: 120g of Erxiancao, 100g of Euonymus euonymus 100g, 20g of Saponin II, 80g of Black Heart Fern, and 40g of Zaiguo;

[0048] Preparation:

[0049] (1) According to the proportion of raw materials, take Xiaoerxiancao, Euonymus daguna, Saponin II of Burnet elm, Fern fern, and Zaiguo, mix them evenly, use ethanol with a concentration of 33% by weight as a solvent, and extract by warm soaking at 37.5°C. The number of extractions is 16 times, each extraction time is 35 hours, and the amount of solvent used each time is 60 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, and concentrates to a relative density of 1.12 , filtered, the medicinal solution passes through...

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Abstract

The invention discloses a drug composition for treating synovitis and a preparation method of the drug composition. The drug composition is prepared by taking herbs of smalllfower seaberry, roots of Denseflower Euonymus, ziyuglycoside II, Concolorous Doryoteris and roots of P. tibetanicum Wolff as crude drugs and proportioning, can be prepared into various dosage forms according to a conventional preparation technology and is remarkable in curative effect on treating the synovitis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating synovitis and a preparation method thereof. Background technique [0002] Osteoarthritis (OA) is a type of disease characterized by loss of local articular cartilage accompanied by varying degrees of osteophyte formation, subchondral bone changes, and synovitis. Synovitis is the earliest symptom in the pathogenesis of osteoarthritis, and most of the pain in patients with knee osteoarthritis is related to synovial inflammation. Knee osteoarthritis is common in middle-aged and elderly people. The main clinical symptoms are knee joint pain during walking, morning stiffness, difficulty going up and down stairs, swelling, bone friction sound, and limited mobility. These are the main causes of lower limb dysfunction in middle-aged and elderly people. . The prevalence of knee osteoarthritis in middle-aged and elderly peop...

Claims

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Application Information

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IPC IPC(8): A61K36/37A61P19/04A61P19/02A61K31/704
CPCA61K36/23A61K31/704A61K36/12A61K36/185A61K36/37A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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