Aryl pyridone compound preparation method
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 周晓芳
- Publication Date
- 2017-06-30
- Estimated Expiration
- Not applicable · inactive patent
Smart Images
Figure 1 
Figure 2 
Figure 3
Abstract
Description
technical field
[0001] The invention relates to a preparation method of a biologically active intermediate compound, more particularly to a preparation method of a pharmaceutical intermediate aryl pyridone compound, which belongs to the technical field of medicine and organic chemical synthesis. Background technique
[0002] The structure of arylpyridone widely exists in natural active compounds and medicines, and this kind of compounds have very important applications in the pharmaceutical industry as synthetic intermediates. The preparation method of aryl pyridone compounds has been paid more and more attention by scientists, and a lot of researches have been done on it. So far, the preparation methods of arylpyridones have been reported in the prior art, such as "Iron catalyzedregio-selective directarylation at C-3position of N-alkyl-2-pyridone" reported by Atanu Modak et al. However, these existing methods still have some defects, such as low product yield, complicated ...