Antibacterial and anti-inflammatory pharmaceutical composition and preparation method thereof

An antibacterial and anti-inflammatory composition technology, which is applied in the field of anti-inflammatory drugs and can solve the problems of severe toxicity and side effects of antibiotics

Inactive Publication Date: 2017-10-27
HEFEI CHUANDI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The invention proposes an antibacterial and anti-inflammatory pharmaceutical composition and a preparation method thereof, which solves the defect that antibiotics have relatively large toxic and side effects in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] An antibacterial and anti-inflammatory pharmaceutical composition, which is composed of the following parts by weight: 52 parts by weight of fenugreek, 26 parts by weight of purslane, 8 parts by weight of dandelion, 9 parts by weight of flea, 8 parts by weight of capillary, and 10 parts by weight of frankincense part, 13 parts by weight of Houttuynia cordata, 12 parts by weight of myrrh and 12 parts by weight of Folium Folium, the preparation method steps of the pharmaceutical composition are as follows:

[0029] (1) get the medicinal materials of the said parts by weight, such as guibangui, purslane, dandelion, flea, capillary, frankincense, houttuynia cordata, myrrh and Folium folium, remove weeds, wash, chop, Add water, extract with ultrasonic frequency 20KHZ, power 14.5KW, control the extraction temperature at 30-50°C, extract for 30-40min, filter the extract through fiber cloth, collect the filtrate, add water to the dregs, ultrasonically extract again for 25-30min,...

Embodiment 2

[0034] An antibacterial and anti-inflammatory pharmaceutical composition, which is composed of the following parts by weight: 50-60 parts by weight of barley, 20-30 parts by weight of purslane, 5-15 parts by weight of dandelion, 5-15 parts by weight of flea, 5-15 parts by weight of Chen, 5-15 parts by weight of frankincense, 15-25 parts by weight of Houttuynia cordata, 5-15 parts by weight of myrrh and 5-15 parts by weight of Daqingye.

[0035] An antibacterial and anti-inflammatory pharmaceutical composition and a preparation method thereof, the steps of the preparation method are as follows:

[0036] (1) get the medicinal materials of the said parts by weight, such as guibangui, purslane, dandelion, flea, capillary, frankincense, houttuynia cordata, myrrh and Folium folium, remove weeds, wash, chop, Add water, extract with ultrasonic frequency 20KHZ, power 14.5KW, control the extraction temperature at 30-50°C, extract for 30-40min, filter the extract through fiber cloth, col...

Embodiment 3

[0040] Embodiment 3: animal toxicology test

[0041] Acute Toxicity Test

[0042] Get 10 experimental mice with half male and female body weights of 20g ± 2g, and the test drug is the powder prepared in Example 2 of the present invention. Every day, for each mouse, 0.33g of the powder is taken, and 1ml of medicinal liquid is prepared for intragastric administration. It is equivalent to 50g / kg of mouse body weight, which is equivalent to 1000 times of human clinical dosage. For 7 consecutive days, the mice were observed to behave normally, and no LD50 was detected, indicating that the pharmaceutical composition of the present invention is non-toxic and safe for clinical use.

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PUM

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Abstract

The invention provides an antibacterial and anti-inflammatory pharmaceutical composition and a preparation method thereof. The antibacterial and anti-inflammatory pharmaceutical composition is prepared from the following components in parts by weight: 50 to 60 parts of herba polygoni perfoliati, 20 to 30 parts of purslane herb, 5 to 15 parts of herba taraxaci, 5 to 15 parts of paris rhizome, 5 to 15 parts of herba artemisiae capillariae, 5 to 15 parts of frankincense, 15 to 25 parts of herba houttuyniae, 5 to 15 parts of myrrh and 5 to 15 parts of folium isatidis. The antibacterial and anti-inflammatory pharmaceutical composition provided by the invention has the advantages of scientific and reasonable components, low price, simple and convenient preparation method, good treatment effect and small toxic and side effect, and is suitable for clinical application.

Description

technical field [0001] The invention belongs to the technical field of anti-inflammatory drugs, in particular to an anti-bacterial and anti-inflammatory pharmaceutical composition and a preparation method thereof. Background technique [0002] It is understood that China is one of the countries with the largest overuse of antibiotics in the world, and its harm to children and the elderly is even more serious. Every year, there are many complaints and exposures about major cases of death and disability caused by antibiotics. The National Food and Drug Administration The bureau also ordered the sales restriction. Natural Chinese herbal medicine has a profound cultural history in antibacterial and anti-inflammatory aspects. Traditional Chinese medicine has successful experience and unique advantages in antibacterial. Prominent role. However, the existing antibacterial traditional Chinese medicine has poor therapeutic effect. Contents of the invention [0003] The invention ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P29/00A61P31/02A61P17/02A61P31/10A61P15/02A61P31/04
CPCA61K36/70A61K36/185A61K36/195A61K36/282A61K36/288A61K36/315A61K36/324A61K36/328A61K36/704A61K36/78A61K36/855A61K36/896A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 秦杰军秦川
Owner HEFEI CHUANDI MEDICAL TECH
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