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Composition for reducing intestinal gas production

一种组合物、肠道的技术，应用在药物组合、羟基化合物有效成分、食品制备中使用的细菌等方向，能够解决没有致力化合物临床研究对比结果等问题

Inactive Publication Date: 2018-01-02
DANONE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Simethicone and activated charcoal are among the most popular such treatments, but few clinical studies devoted to these compounds have produced comparable (if not negative) results

Method used

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  • Composition for reducing intestinal gas production
  • Composition for reducing intestinal gas production
  • Composition for reducing intestinal gas production

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0087] Materials and methods

[0088] Subjects and Study Design

[0089] IBS patients or subgroups of IBS patients are generally considered by the European Food Safety Authority to be suitable study populations to substantiate gastrointestinal complaints for the general population (EFSA Journal 2011;9(4):1984). All participants underwent a combined nutrient and lactulose stress test to assess gastrointestinal symptoms, as well as exhaled H 2 The amount of intestinal gas production as an objective indicator. Adult subjects meeting Rome III criteria for irritable bowel syndrome (IBS) were prospectively admitted to a tertiary care outpatient clinic. Diagnosis is based on typical clinical presentation and additional investigations if deemed necessary. IBS subtypes were classified according to the Rome III criteria based on the following stool shape classification table features: IBS with constipation (IBS-C), IBS with diarrhea (IBS-D), mixed IBS (IBS-M) or undifferentiated Sub...

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PUM

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Abstract

The present invention relates to a composition comprising Bifidobacterium bacteria for use for reducing intestinal gas production in an individual.

Description

technical field [0001] The present invention relates to compositions for reducing intestinal gas production in an individual. Background technique [0002] Excessive intestinal gas is one of the causes of gastrointestinal discomfort that can significantly affect health and quality of life. Gas-related symptoms are the most common and bothersome digestive symptoms, affecting 15-20% of the general population and up to 90% of irritable bowel syndrome (IBS) patients. IBS patients or subgroups of IBS patients are generally considered by the European Food Safety Authority to be an appropriate study population to substantiate gastrointestinal complaints applicable to the general population (EFSA Journal 2011;9(4):1984). There is currently no effective or sustainable treatment for excessive intestinal gas production. [0003] The main source of intestinal gas is the carbohydrate catabolism activity of colonic bacteria, which produces a large amount of gas, mainly hydrogen (H 2 ),...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/745A61K31/7016A61K31/702A61K31/047A61K31/715A61K31/733A61K31/718A61P1/14A23C9/123
CPCA61K31/047A61K31/7016A61K31/702A61K31/715A61K31/718A61K31/733A23L33/135A61K35/745A61P1/14A23V2400/515A61K35/74A61P43/00
Inventor 鲍里斯·勒内韦E·罗谢德尼·居约内
Owner DANONE
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