Composition for reducing blood uric acid of hyperuricemia

Abstract

The invention discloses a composition for reducing blood uric acid of hyperuricemia. The composition is prepared from the following ingredients in parts by weight: 25 to 100 parts of orange extracts,50 to 200 parts of grape seed extracts, 5 to 20 parts of vitamin E, 2.5 to 10 parts of vitamin B6, 5 to 20 parts of nicotinic acid, 50 to 200 parts of zinc gluconate and 500 to 2000 parts of potassiumcitrate. The animal effect evaluation result shows that the composition provided by the invention can obviously improve the urine pH of a rat with hyperuricemia; the 24h urine discharge quantity is obviously improved; the serum total anti-oxidization capability is improved; the lipid peroxide content is obviously reduced; the serum xanthine oxidase activity is reduced; the blood uric acid level is obviously reduced. The animal experiment result shows that when a proper quantity of the composition is supplied to the model rat with the hyperuricemia, the body anti-oxidization capability can beobviously improved; the blood uric acid is reduced.

Description

technical field [0001] The invention relates to a functional composition, in particular to a composition for reducing blood uric acid in hyperuricemia. Background technique [0002] Hyperuricemia (HUA) refers to a heterogeneous disease caused by purine metabolism disorder and / or uric acid excretion disorder, which is mainly characterized by elevated blood uric acid. In recent years, with the improvement of people's living standards and changes in dietary structure, the prevalence of hyperuricemia in my country has a very obvious upward trend. According to a survey data in 2009, the prevalence rate of hyperuricemia in Shanghai was 10.0%, the prevalence rate of hyperuricemia in 1120 subjects in Beijing was 17.86%, and the prevalence rate in Guangzhou ranked first in the country. 27.9%, female 12.4%, the total prevalence rate is as high as 21.81%. Hyperuricemia is associated with cardiovascular disease, chronic kidney disease, and metabolic syndrome, and is an important bioch...

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Problems solved by technology

[0003] At present, the treatment of hyperuricemia is mainly based on drugs, including relying on the xanthine oxidase inhibitor allopurinol and uricosuric drugs probenecid, benzbromarone, etc. Most of these drugs were developed in the 1950s, and Toxic and side effects are large, and patients often cannot tolerate it, which limits its use to a certain extent

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