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A method and system for non-rigid registration of multimodal medical images based on deep learning

A non-rigid registration, medical image technology, applied in the field of non-rigid multi-modal medical image registration, can solve the problem of low registration accuracy of non-rigid multi-modal medical images

Active Publication Date: 2020-09-18
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology

[0006] In view of the above defects or improvement needs of the prior art, the present invention provides a method and system for non-rigid registration of multi-modal medical images based on deep learning, thereby solving the problem of registration accuracy of existing non-rigid multi-modal medical images. low technical issues

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  • A method and system for non-rigid registration of multimodal medical images based on deep learning
  • A method and system for non-rigid registration of multimodal medical images based on deep learning
  • A method and system for non-rigid registration of multimodal medical images based on deep learning

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Embodiment 1

[0089] Step 1 trains the PCANet network. Input N medical images For each pixel of each image, take k without interval 1 ×k 2 The block; vectorize the obtained block and perform de-average. Combining all the resulting vectors together will result in a matrix. Calculate the eigenvector of this matrix, and sort the eigenvalues ​​from large to small, and take the first L 1 The eigenvectors corresponding to the eigenvalues. Will L 1 The eigenvectors are matrixed, and the L of the first layer will be obtained 1 convolution template. Convolving the convolution template with the input image will result in NL 1 images. will this NL 1 The image is input into the second layer PCANet, according to the processing method of the first layer, we will get the L of the second layer PCANet 2 Convolution templates, and get NL 1 L 2 images.

[0090] Step 2 Obtain a PCANet-based structural representation (PCANet-based structural representation, PSR for short) according to the PCANet ...

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Abstract

The invention discloses a non-rigid registration method and system for multi-mode medical images based on deep learning. The registration method includes: training PCANet through a large amount of medical data; inputting floating images and reference images into the trained PCANet, Obtaining the structural representation diagram of the floating image and the reference image; finally obtaining the registration image according to the reference image and the structural representation diagram of the floating image. The invention utilizes the PCANet deep learning network to construct the structural representation diagram of the image, transforms the registration problem of non-rigid multi-mode medical images into the registration problem of single-mode medical images, and greatly improves the accuracy and accuracy of non-rigid multi-mode medical image registration. robustness.

Description

technical field [0001] The invention belongs to the field of image registration in image processing and analysis, and more specifically relates to a non-rigid multi-mode medical image registration method and system. Background technique [0002] Non-rigid multimodal medical image registration is important for medical image analysis and clinical research. Due to the different principles of various imaging technologies, each has its own advantages in reflecting the information of the human body. Computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound imaging can reveal anatomical information about organs. As a functional imaging modality, positron emission tomography (PET) can reveal metabolic information, but cannot clearly provide anatomical information of organs. Multimodal image fusion technology can combine the information of different modal images, so as to obtain more accurate diagnosis and better treatment. [0003] The purpose of image registrati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/33G06N3/04
CPCG06T7/33G06T2207/10081G06T2207/10088G06N3/045
Inventor 张旭明朱星星
Owner HUAZHONG UNIV OF SCI & TECH
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