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Preparation method of plant fruit kernel oral solution for treating helicobacter pylori

A technology of Helicobacter pylori and fruit stone oral liquid, which is applied in the field of preparation of plant fruit stone oral liquid, can solve the problems of the influence of Hp in the stomach on the therapeutic effect of antibacterial drugs, troubles the gastroenterology community, antibacterial drug resistance and the like, and achieves a broad spectrum. Anti-Helicobacter pylori, high activity in aqueous solution, improving symptoms

Active Publication Date: 2018-10-09
TIANJIN YUNXIN SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] 2. Influence of Hp in the stomach on the therapeutic effect of antibacterial drugs
[0010] 3. The problem of antimicrobial resistance
However, the current method of eradicating Helicobacter pylori is expensive, and what is more serious is that with the widespread use of antibiotics, more and more drug-resistant Helicobacter pylori strains have become a major problem in the field of gastroenterology.

Method used

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  • Preparation method of plant fruit kernel oral solution for treating helicobacter pylori

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] A preparation method of oral liquid for treating Helicobacter pylori includes the following steps:

[0044] 1) Select plant polysaccharides with anti-Helicobacter pylori activity and put them into the stone vinegar refined liquid. The input amount of plant polysaccharides accounts for 5% of the quality of the stone vinegar refined liquid. Stir evenly to obtain the fruit stone polysaccharide vinegar liquid; The polysaccharide is a mixture of wolfberry polysaccharide and hericium erinaceus polysaccharide, and the mass ratio of the two is 1:2.

[0045] 2) Add papain to the fruit pit polysweet and vinegar solution obtained in step 1) for enzymatic hydrolysis, the reaction temperature is 50°C, the reaction time is 45 minutes, and the amount of enzyme added is 600 U / mL;

[0046] 3) Filter the enzymatically hydrolyzed fruit stone polysaccharide and vinegar liquid processed in step 2) to obtain an oral liquid for treating Helicobacter pylori.

[0047] The refined liquid of the stone vi...

Embodiment 2

[0055] A preparation method of oral liquid for treating Helicobacter pylori includes the following steps:

[0056] 1) Select plant polysaccharides with anti-Helicobacter pylori activity and put them into the stone vinegar refined liquid. The input amount of plant polysaccharides accounts for 10% of the quality of the stone vinegar refined liquid. Stir evenly to obtain the fruit stone polysaccharide vinegar liquid; The polysaccharide is a mixture of wolfberry polysaccharide and hericium erinaceus polysaccharide, and the mass ratio of the two is 1:2.

[0057] 2) Add papain to the fruit pit polysweet and vinegar solution obtained in step 1) for enzymatic hydrolysis, the reaction temperature is 50°C, the reaction time is 45 minutes, and the amount of enzyme added is 600 U / mL;

[0058] 3) Filter the enzymatically hydrolyzed fruit stone polysaccharide and vinegar liquid processed in step 2) to obtain an oral liquid for treating Helicobacter pylori.

[0059] The refined liquid of the stone v...

Embodiment 3

[0067] A preparation method of a plant fruit pit oral liquid for treating Helicobacter pylori includes the following steps:

[0068] 1) Select plant polysaccharides with anti-Helicobacter pylori activity and put them into the stone vinegar refined liquid. The input amount of plant polysaccharides accounts for 20% of the quality of the stone vinegar refined liquid. Stir evenly to obtain the fruit stone polysaccharide vinegar liquid; The polysaccharide is a mixture of wolfberry polysaccharide and hericium erinaceus polysaccharide, and the mass ratio of the two is 1:2.

[0069] 2) Add papain to the fruit pit polysweet and vinegar solution obtained in step 1) for enzymatic hydrolysis, the reaction temperature is 50°C, the reaction time is 45 minutes, and the amount of enzyme added is 600 U / mL;

[0070] 3) Filter the enzymatically hydrolyzed fruit stone polysaccharide and vinegar liquid processed in step 2) to obtain an oral liquid for treating Helicobacter pylori.

[0071] The refined liq...

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Abstract

The invention provides a preparation method of a plant fruit kernel oral solution for treating helicobacter pylori. The preparation method comprises the following steps: 1) selecting plant polysaccharide with helicobacter pylori resisting activity and adding the plant polysaccharide into fruit kernel vinegar refined liquid, wherein the adding amount of the plant polysaccharide accounts for 5 to 30percent of the mass of the fruit kernel vinegar refined liquid; uniformly stirring to obtain fruit kernel polysaccharide vinegar; 2) adding plant proteinase into the fruit kernel polysaccharide vinegar obtained by step 1) and carrying out enzymolysis reaction, wherein the reaction temperature is 50 DEG C to 60 DEG C, the reaction time is 30 to 45 minutes and the adding amount of an enzyme is 400to 600U / mL; 3) filtering the fruit kernel polysaccharide vinegar subjected to enzymolysis in step 2) to obtain the oral solution for treating the helicobacter pylori. The oral solution provided by theinvention has very strong antibacterial and anti-inflammatory effects and has a relatively strong inhibition effect on the helicobacter pylori.

Description

Technical field [0001] The invention belongs to the technical field of oral liquids for treating Helicobacter pylori, and in particular relates to a preparation method of a plant fruit pit oral liquid for treating Helicobacter pylori. Background technique [0002] Survey results confirm that nearly half of the world’s population is infected with Helicobacter pylori, which is highly infectious and can be spread through hands, dirty tableware, dirty food, feces, etc. The treatment of Helicobacter pylori symptoms is generally formulated according to the patient’s condition and the differences in regions and populations. In general, a single antibacterial drug is not recommended at present because its cure rate is relatively low and it is easy to produce resistance. Some people think that the treatment of Helicobacter pylori symptoms is an easy problem. In fact, the treatment effect is not very satisfactory. Moreover, there is currently a lack of suitable Helicobacter pylori animal m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K9/08A61P31/04A61P1/00A61P1/04A61K31/715
CPCA61K9/0095A61K31/715A61K36/725A61K36/734A61K36/736A61P1/00A61P1/04A61P31/04A61K2300/00
Inventor 王为王蒙兰涛
Owner TIANJIN YUNXIN SCI & TECH DEV
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