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Application of licochalcone A to preparation of medicine for treating necrotic enteritis

A chicken necrotic enteritis, licorice chalcone technology, applied in the field of medicine, to achieve the effect of reducing the degree of pathological changes and good therapeutic effect

Active Publication Date: 2018-11-20
HUBEI WUDANG ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, up to now, there is no relevant research on the use of licochalcone A in the treatment of chicken necrotic enteritis caused by Clostridium perfringens at home and abroad.

Method used

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  • Application of licochalcone A to preparation of medicine for treating necrotic enteritis
  • Application of licochalcone A to preparation of medicine for treating necrotic enteritis
  • Application of licochalcone A to preparation of medicine for treating necrotic enteritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The application of the licochalcone A in the preparation of the medicine for treating chicken necrotic enteritis, the licochalcone A is used as the active agent to prepare any pharmaceutically acceptable dosage form.

Embodiment 2

[0032] Licochalcone A described treatment chicken necrotic enteritis refers to the necrotic enteritis caused by bacteria.

Embodiment 3

[0034] The treatment of chicken necrotic enteritis described in Licochalcone A refers to the necrotic enteritis caused by Clostridium perfringens.

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PUM

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Abstract

The invention discloses application of licochalcone A to preparation of a medicine for treating necrotic enteritis. A clostridium perfringens sliding motion inhibition test, a biofilm formation inhibition test and a chick necrotic enteritis model test verify that the licochalcone A has protective effect on chicken necrotic enteritis caused by infection of clostridium perfringens. Due to abuse of the traditional antibiotics and bacterial medicine resistance, the licochalcone A has the characteristics of high curative rate, no medicine resistance and no medicine residues, and the licochalcone Acan improve the selectivity of the used medicines and has important significance in developing new medicines when being used for treating the chicken necrotic enteritis.

Description

technical field [0001] The invention discloses the use of licochalcone A in treating chicken necrotic enteritis, relates to the application of licochalcone A in preparing medicines for treating chicken necrotic enteritis, and belongs to the technical field of medicine. Background technique [0002] Clostridium perfringens is an anaerobic Gram-positive bacillus, which widely exists in soil, water, food, human and animal feces, livestock feed and animal intestines in nature, and is the normal intestinal flora of humans and animals , an opportunistic pathogen. At present, according to the different exotoxins it secretes, it is divided into 5 serotypes, A-E, and poultry are mainly infected with type A and type C Clostridium perfringens, especially type A. After Clostridium perfringens infects poultry, it mainly causes necrotic enteritis, and its symptoms are manifested as listlessness, loose feathers, loss of appetite or waste, hematochezia, and severe decline in production per...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/12A61P1/00A61P31/04
CPCA61K31/12A61P1/00A61P31/04
Inventor 邓旭明刘水王建锋王峻陈国明张建
Owner HUBEI WUDANG ANIMAL PHARMA
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