A stereotaxic device for the brain

A technology of stereotaxic and positioning device, applied in the field of biological experiments, can solve the problems of shortening the survival time of animals, inaccurate experimental results, and failing to achieve expected results, and achieve the effects of maintaining the quality of life, preventing tilt, and increasing stability.

Active Publication Date: 2021-02-23
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Medical or biological experiments often involve partitioning the brain tissue of target animals (such as rats, etc.) in order to study the functions of different regions of the brain. The most commonly used method is to implant guide pins in the target brain area. Now biological The method of implanting the guide pin in the experiment mainly adopts the method of craniotomy. After the craniotomy, the guide pin is implanted into the brain tissue. The craniotomy is easy to cause damage, bleeding, inflammation and infection to the skull and brain tissue, shortening the survival time of animals. As a result, the experimental results are inaccurate and the expected results cannot be achieved, so a device is needed to insert the guide needle into the skull at a fixed point without destroying the brain tissue

Method used

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  • A stereotaxic device for the brain
  • A stereotaxic device for the brain
  • A stereotaxic device for the brain

Examples

Experimental program
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Effect test

Embodiment 1

[0034] A brain stereotaxic device, comprising a base on which a target animal fixing device, a guide pin positioning device and a support plate 4 are arranged, the target animal fixing device includes a fixing groove 5 arranged on the bottom plate 1 and a fixing groove 5 matched The slot cover 6, the fixing slot is used to fix the head of the target animal; the slot cover 6 is provided with a through hole 52 and is hingedly connected with the base plate 1, and the fixing slot is provided with a fixture for fixing the slot cover 6, such as a lockset 51 , buckles, etc. The trunk fixing groove 10 and the groove cover 6 matched with the trunk fixing groove 10 can also be set on the bottom plate 1, and the cover 6 can quickly fix the head and trunk of the target animal, and the target animal exposes the head through the through hole , for subsequent drilling to increase the stability of the target animal.

[0035] The guide needle positioning device includes a horizontal moving de...

Embodiment 2

[0037] A positioning method, using the brain stereotaxic device described in embodiment 1 as a positioning tool, comprising the following steps:

[0038] The target is fixed in the fixing groove of the bottom plate and partially exposed through the through hole;

[0039] Take the target insertion point of the guide pin as the anchor point to obtain the position of the anchor point;

[0040] Drive the support plate 4 to move horizontally, so that the drill bit of the drilling tool moves to the top of the positioning point;

[0041] Drive the support plate to move vertically, so that the drill bit of the drilling tool is close to the positioning point;

[0042] Drive the support plate to rotate in the horizontal plane, so that the drill bit of the drilling tool moves to the positioning point for drilling;

[0043] Drive the support plate to rotate inwardly on the horizontal plane, so that the guide pin moves to the position of the positioning point, and the guide pin is insert...

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Abstract

The invention discloses a brain stereo positioning device and positioning method. The positioning device comprises a base. A target animal fixing device, a guide needle positioning device and a support plate are arranged on the base. The guide needle positioning device comprises a horizontal movement device. The support plate is fixed on the horizontal movement device through a connecting device.A guide needle holder and a drilling tool are arranged on the support plate, and the connecting device can drive the support plate to move vertically and rotate in a horizontal plane. A guide needle can be inserted into a target object from a target insertion point accurately, so as to maintain the life quality and survival time of an animal to the maximum extent, and to increase the accuracy of experimental results. According to the invention, the target insertion point of the guide needle inserted into the target object can be positioned accurately. According to the positioning method, the guide needle is inserted into a skull after drilling a hole with the drilling tool so as to maintain the life quality and the survival time of the animal to the maximum extent and to increase the accuracy of the experimental results.

Description

technical field [0001] The invention relates to the field of biological experiments, in particular to a brain stereotaxic device. Background technique [0002] Medical or biological experiments often involve partitioning the brain tissue of target animals (such as rats, etc.) in order to study the functions of different regions of the brain. The most commonly used method is to implant guide pins in the target brain area. Now biological The method of implanting the guide pin in the experiment mainly adopts the method of craniotomy. After the craniotomy, the guide pin is implanted into the brain tissue. The craniotomy is easy to cause damage, bleeding, inflammation and infection to the skull and brain tissue, shortening the survival time of animals. As a result, the experimental results are inaccurate and the expected results cannot be achieved, so a device is needed to insert the guide needle into the skull at a fixed point without destroying the brain tissue. Contents of t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61D3/00A61D1/00
CPCA61D1/00A61D3/00A61D2003/003
Inventor 李艺杰乔明琦宋春红薛玲王杰琼郭英慧孙鹏魏盛夏小雯孙亚蔡亚伟胡明会
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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