Gene expression data classifier

A gene expression and classifier technology, applied in the field of gene expression data classifiers, can solve problems such as increased overfitting, less cancer training data, and difficulty in representing cancer information well, achieving enhanced classification performance and enhanced classification performance , improve the effect of negative impact

Inactive Publication Date: 2019-05-21
HARBIN INST OF TECH SHENZHEN GRADUATE SCHOOL
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Problems solved by technology

Therefore, the high dimensionality of the feature space increases the risk of overfitting, since the number of genes is much larger than the number of samples
The second challenge is the lack of tissue samples, and it is difficult for existing methods to represent cancer information well because there is little training data for cancer
In the past five years, although the above-mentioned multi-task-based deep learning model has achieved success in computer vision and biomedical image analysis, the existing methods are all independently learning expression and obtaining learning results.

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Embodiment Construction

[0024] The specific implementation manners of the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0025] The structure attachment of a kind of gene expression data classifier that the present invention proposes figure 2 shown.

[0026] A gene expression data classifier, characterized in that the classifier comprises: an input layer, a first hidden layer, a second hidden layer and an output layer;

[0027] The input layer includes a plurality of input units, each input unit receives a data set, and the data unit is connected to a local hidden unit in the first shared unit;

[0028] The first hidden layer includes local hidden units having the same number of input units in the input layer and a first shared hidden unit, the local hidden units are correspondingly conne...

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Abstract

The invention relates to the field of electric data processing, in particular to a gene expression data classifier. On the basis of a traditional multi-task deep learning processing method, a gene expression data classifier with an input layer, a first hidden layer, a second hidden layer and an output layer is designed. Particularly, a shared hiding unit is arranged on the first hidden layer and the second hidden layer, so that the classifier can process gene expression data which come from different data sets and have different identifiers. The problem that tissue samples are insufficient when the gene expression data are classified is effectively solved. Adverse effects caused by the introduction of high feature space dimensions are reduced.

Description

technical field [0001] The invention relates to the field of electrical data processing, in particular to a gene expression data classifier. Background technique [0002] The study of the relationship between gene expression profiles and cancer / disease states is a very important content in biological and medical tasks. For example, comparing diseased and normal tissue can improve understanding of pathology and help identify different tissues (cancerous or normal) because gene expression data can provide clues to tissue phenotype, function, and physiological processes. However, considering the quantity and complexity of gene expression data, traditional biological experiments cannot handle such data. [0003] Table 1 Examples of gene expression data [0004] [0005] Table 1 is an example of gene expression data. Gene expression data is usually expressed using a matrix of n rows and m columns, these rows represent characteristics (genes), and these columns represent sam...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B25/10G16H50/70G06K9/62
Inventor 廖清丁烨漆舒汉蒋琳王轩
Owner HARBIN INST OF TECH SHENZHEN GRADUATE SCHOOL
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