33 results about "Processed Genes" patented technology

The invention relates to an isolated component analysis and linear discriminant analysis combined cancer forecasting method which particularly includes the following steps: (1) pre-processing gene micro-array data with the filtering technology, (2) converting the pre-processed gene micro-array data with the isolated component analysis technology to obtain an isolated component set, (3) processing the isolated component set with the linear discriminant analysis technology, and projecting the gene micro-array data into low-dimensional space with the optimal separability, and (4) training a nearest neighbor classifier through the projected gene micro-array data to generate a classifier model. According to the isolated component analysis and linear discriminant analysis combined cancer forecasting method, the gene micro-array data are filtered and processed, implicit information of the gene micro-array data is mined through isolated component analysis, and the gene micro-array data are projected to the low-dimensional space with the optimal separability through linear discriminant analysis, the cancer forecasting accuracy is improved, and the cancer forecasting time is shortened.

The invention provides methods of compressing and decompressing gene sequences and a device of compressing the gene sequence. The method of compressing the gene sequence includes: generating a variation reference sequence according to high-frequency variation information and a standard reference sequence; and compressing the to-be-processed gene sequence according to a matching result of the to-be-processed gene sequence and the variation reference sequence to obtain the compressed gene sequence. According to the above-mentioned methods of compressing and decompressing the gene sequences and the above-mentioned device of compressing the gene sequence, a rate of compression for the gene sequence can be increased, thus storage space of the gene sequence is reduced, and copying and transmission for the gene sequence are facilitated.

The invention discloses a method and system for discovering molecular markers based on transcriptome temporal dynamic changes and gene function correlation. Through multi-chronological sampling of samples and high-throughput transcriptome sequencing technology, target pathophysiological processes and control pathophysiological processes can be obtained. The dynamic time-series transcriptome changes of the process; through gene function association analysis, the correlation strength between the differential co-expression set and the gene set of the target pathophysiological process is evaluated, so as to discover robust and reliable markers with pathophysiological significance in the omics data. The present invention makes full use of the time-series correlation and the internal correlation of omics indicators. The process of marker discovery is mutually supported and verified by different types of information, and the robustness is high. Therefore, the requirements for data measurement accuracy and method parameter optimization are relatively low, and there is no It can also be used effectively by personnel with rich experience in experiments and analysis.

The invention provides a nucleotide specific to O-antigens of Escherichia coli O140, a full sequence of gene cluster in Escherichia coli O140, controlling O-antigen synthesis, such as the separated nucleotide shown in SEQ IN No.1, with a overall length of 14009 basic groups; or a nucleotide in SEQ IN No.1 having one or many inserted, deleted or substituted basic groups and simultaneously maintaining functions of the separated nucleotide; also including an oligonucleotide coming from glycosyltransferase gene and oligosaccharide unit-processing gene in the O-antigen gene cluster of Escherichia coli O140; by PCR, the invention verifies that oligonucleotide has specificity to all the O-antigens of Escherichia coli O140; the invention also discloses a method of using the oligonucleotide to detect and identify Escherichia coli O140 in the human body and environment.