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35 results about "Insertional mutagenesis" patented technology
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In molecular biology, insertional mutagenesis is the creation of mutations of DNA by the addition of one or more base pairs. Such insertional mutations can occur naturally, mediated by viruses or transposons, or can be artificially created for research purposes in the lab.
DNA vectors and elements for sustained gene expression in eukaryotic cells
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel elements that further improve expression. The gene transfer systems can be used in methods, for example, gene expression, bioprocessing, gene therapy, insertional mutagenesis, or gene discovery.
Owner:DNA TWOPOINTO INC
Transposition of nucleic acid constructs into eukaryotic genomes with a transposase from amyelois
ActiveUS12590319B2Polypeptide with localisation/targeting motifPeptide/protein ingredientsHeterologousProcessed Genes
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and transposases that further improve expression. Further disclosed are vectors that can be used in a gene transfer system for stably introducing nucleic acids into the DNA of a cell. The gene transfer systems can be used in methods, for example, gene expression, bioprocessing, gene therapy, insertional mutagenesis, or gene discovery.
Owner:DNA TWOPOINTO INC