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Gene data processing method and device, computer equipment and storage medium

A genetic data and processing method technology, applied in the computer field, can solve problems such as sample contamination, experimenter's operation error, unreliable test results, etc., and achieve high specificity and high sensitivity

Active Publication Date: 2022-07-01
SHANGHAI ORIGIMED CO LTD +1
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  • Abstract
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Problems solved by technology

[0002] In the high-throughput sequencing of tumor DNA samples, samples are often contaminated due to various reasons, such as uncleaned blades / brushes / microtome between wax blocks during slicing, residual samples from the spreader, and patients who have had blood transfusions Or organ transplantation and experimenter's operation errors lead to sample contamination, which will directly lead to unreliable test results

Method used

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  • Gene data processing method and device, computer equipment and storage medium
  • Gene data processing method and device, computer equipment and storage medium
  • Gene data processing method and device, computer equipment and storage medium

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Embodiment Construction

[0041] In order to make the purpose, technical solutions and advantages of the present application more clearly understood, the present application will be described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application.

[0042] The genetic data processing methods provided in the embodiments of the present application can be applied to, for example, figure 1 in the application environment shown. The terminal 102 communicates with the server 104 through the network. The data storage system may store data that the server 104 needs to process. The data storage system can be integrated on the server 104, or it can be placed on the cloud or other network server. The server 104 obtains the gene data to be processed, extracts the gene data to be processed, and obtains the homozygous mutatio...

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Abstract

The invention relates to a gene data processing method and device, computer equipment, a storage medium and a computer program product. The method comprises the following steps: acquiring gene data to be processed; extracting the to-be-processed gene data to obtain information of a homozygous mutation site of the to-be-processed gene data; obtaining a preset screening condition, and screening suspected pollution sites in the to-be-processed gene data according to the screening condition and the information of the homozygous mutation sites; and calculating the pollution rate of the to-be-processed gene data according to the suspected pollution sites. By adopting the method, the pollution rate can be accurately calculated, and the reliability of detection results is improved.

Description

technical field [0001] The present application relates to the field of computer technology, and in particular, to a data processing method, apparatus, computer equipment, storage medium and computer program product. Background technique [0002] During high-throughput sequencing of tumor DNA samples, the samples are often contaminated for various reasons, such as the blade / brush / microtome is not cleaned between the wax blocks during the sectioning process, the sample remains in the slicer, and the patient has undergone blood transfusion. Or the contamination of samples caused by organ transplantation and operator errors, which will directly lead to unreliable test results. SUMMARY OF THE INVENTION [0003] Based on this, it is necessary to provide a genetic data processing method, device, computer equipment, computer-readable storage medium and computer program product that can accurately calculate the contamination rate and improve the reliability of the detection result ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B20/50G16B50/00
CPCG16B20/50G16B50/00Y02P90/30
Inventor 董筱微张恒柳文进
Owner SHANGHAI ORIGIMED CO LTD
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