Combined application of CNS (central nerves system) inhibitor and opioids in endoscopy
A technology for opioid substances and gastroscopy, which is applied in the direction of drug combinations, anesthetics, medical preparations containing active ingredients, etc.
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[0038] Example 1: Clinical research on remimazolam combined with fentanyl for gastroscopy
[0039] 1. Test drugs
[0040] Remimazolam tosylate for injection, the specification is 36mg / branch (calculated as free base), when in use, add 36ml of 0.9% normal saline to each cartridge, and the final configuration is 36ml of injection solution with a concentration of 1mg / ml;
[0041] Commercially available propofol injection;
[0042] Commercially available fentanyl injection.
[0043] 2. Inclusion criteria
[0044] 1) Age 18-60 years old, gender is not limited;
[0045] 2) Patients receiving routine gastroscopy diagnosis and treatment;
[0046] 3) The ASA score is grade I or grade II;
[0047] 4) 18kg / m 2 2 .
[0048] 3. Research groups
[0049] The remimazolam tosylate for injection group was the experimental group, and the propofol group was the control group.
[0050] 4. Test method
[0051] Complete routine preparations before gastroscopy (generally fasting for at leas...
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