Tail suspension mouse cage

Abstract

The invention discloses a tail suspension mouse cage which comprises at least one mouse cage unit, mouse suspension cavities are limited in the mouse cage units, partition plates are slidably arrangedin the mouse suspension cavities, the mouse suspension cavities are divided into two mouse suspension spaces, the sizes of the two mouse suspension spaces can be adjusted by sliding the partition plates, suspension devices are mounted above the mouse suspension spaces and comprise sliding cross rods, suspension springs, suspension rings and tail tying mechanisms, the sliding cross rods are slidably arranged at the tops of the mouse suspension spaces, the suspension rings are arranged on the sliding cross rods in a sleeving manner, one end of each suspension spring is connected with the corresponding suspension ring, the other end of each suspension spring is connected with the corresponding tail tying mechanism, the tail of an experimental mouse can be suspended by the tail tying mechanism, the tail is firmly fixed, wound is omitted, mouse tail damage and mouse tail dividing injury or mouse tail avascular necrosis can be omitted, and the number of samples and accuracy of experimentalresults are ensured.

Description

technical field [0001] The invention relates to a laboratory simulation device, in particular to a tail-suspended mouse cage. Background technique [0002] Disuse muscular atrophy is a common complication in clinical practice. Hypokinesia, air weightlessness, braking, etc. can all cause obvious disuse muscular atrophy and affect the motor function of the human body. Therefore, how to prevent the occurrence of disuse muscular atrophy is particularly important. Muscle atrophy induced by tail-suspended mice is a commonly used animal model, which is helpful for the study of muscle atrophy. [0003] Existing tail suspension squirrel cages have many defects: [0004] 1. The existing methods of tail suspension for experimental rats mainly use rope ligation, tape fixation or clip fixation. However, because the rat tail is conical, with a thick root and a thin end, it is necessary to fix the suspension rope at the end of the rat tail when hanging. When hanging upside down, the ex...

AI Technical Summary

Problems solved by technology

When hanging upside down, the experimental rat will swing and struggle, and the tail of the rat will easily fall off if it is tied with a rope or directly suspended with ordinary clips

In addition, when the weight of the mouse is large, the hanging mouse tail is also very easy to fall off

However, if the rope is ligated too tightly, or the clip is over-clamped, the tail of the rat will be damaged, the tail will be severed, or the tail ischemic necrosis, and the experiment cannot be continued, which will affect the experimental results.

[0005] 2. The size of the cage containing the experimental mice is fixed, but the size of the experimental mice is not uniform, and with the increase of the experimental time, the experimental mice will grow up and gain weight, and the fixed size of the cage will affect the experimental results. Reduce experimental efficiency and increase experimental cost

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