Ophthalmic product and masking method

An ophthalmology and product technology, applied in the field of ophthalmic products and masking, can solve problems such as increased odor and achieve the effect of specific odor inhibition

Pending Publication Date: 2020-08-11
LION CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

On the other hand, active ingredients such as fat-soluble vitamin A are attracting attention as acti

Method used

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  • Ophthalmic product and masking method
  • Ophthalmic product and masking method
  • Ophthalmic product and masking method

Examples

Experimental program
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Embodiment 2

[0171] In Example 2 and Comparative Example 4, the size of the enclosure was changed so that it reached the ratio of the internal space in the table to the volume of the container. In Comparative Example 3, the composition amount (mL) / body capacity (mL) in the table was taken , to achieve a space ratio. In Comparative Example 5, an oxygen-impermeable material was used as the main body.

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Abstract

Provided is an ophthalmic product obtained by: housing, in a container, an ophthalmological composition comprising (A) an easily-oxidizable substance, (B) a refreshing agent, (C) a non-ionic surfactant, and (D) at least one component selected from dibutyl hydroxytoluene, dibutyl hydroxyanisole, propyl para-hydroxybenzoate, butyl para-hydroxybenzoate, and chlorobutanol; and enclosing and sealing, by an enclosing body, the container together with an iron-based oxygen absorber. Regarding the ophthalmic product, the capacity of the main body thereof is 1-25 mL, the oxygen permeability of the mainbody is at least 10 cc/(m2 24 hr atm), and the volume of space formed between the enclosing body and the container is at most 200 V/V% with respect to the volume of the container.

Description

technical field [0001] The present invention relates to an ophthalmic product and a masking method in which the odor of an oxygen absorbing agent is suppressed. Background technique [0002] As a method for stabilizing easily oxidizable components, the use of an oxygen absorbing agent is known. It is known that in the field of eye drops, by enclosing the eye drops and the oxygen absorbing agent contained in the container in the surrounding body, the oxygen in the container is absorbed, and the easily oxidizable substances in the eye drops can be stabilized (Japanese Patent Laid-Open Publication No. 6-40907 bulletin). On the other hand, active ingredients such as fat-soluble vitamin A are attracting attention as active ingredients in the treatment of cornea, conjunctiva, nasal mucosa, and pharynx. Flavor increased. [0003] [Prior Art Literature] [0004] 【Patent Literature】 [0005] [Patent Document 1] Japanese Patent Application Laid-Open No. 6-40907 Contents of the ...

Claims

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Application Information

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IPC IPC(8): A61K47/10A61J1/14A61K9/08A61K31/07A61K31/22A61K47/08A61K47/14A61K47/26A61K47/44A61L9/04A61P3/02A61P27/02B65D81/05
CPCA61J1/14A61K9/08A61K31/07A61K31/22A61K47/08A61K47/10A61K47/14A61K47/26A61K47/44A61L9/04A61P3/02A61P27/02B65D81/05Y02W90/10A61K47/20
Inventor 内藤香菜奥村隆石井玲子
Owner LION CORP
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