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Integrated sample processing system with variable workflows

A sample processing system, technology for biological samples, applied in the field of integrated sample processing systems with variable workflow

Pending Publication Date: 2020-09-15
BECKMAN COULTER INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, MS may not be the best method for analyzing all types of biological samples in every situation

Method used

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  • Integrated sample processing system with variable workflows
  • Integrated sample processing system with variable workflows
  • Integrated sample processing system with variable workflows

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Experimental program
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Embodiment Construction

[0030] Embodiments of the invention can be used to detect the presence, absence or concentration of an analyte in a biological sample. Biological samples such as biological fluids may include, but are not limited to, blood, plasma, serum, or other bodily fluids or excretions, such as, but not limited to, saliva, urine, cerebrospinal fluid, tears, sweat, gastrointestinal fluid, amniotic fluid, mucosal fluid, pleural fluid, Sebum oil, breath, etc.

[0031] The term "analyzer" may include any suitable instrument capable of analyzing a sample, such as a biological sample. Examples of analyzers include mass spectrometers, immunological analyzers, hematology analyzers, microbiology analyzers, and / or molecular biology analyzers.

[0032] The term "measured value" may include a specific value obtained relative to the analysis of a biological sample. Measurements may be determined by one or more analyzers, or by an information management device that obtains data from one or more anal...

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PUM

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Abstract

One embodiment of the invention is directed to a sample processing system for analyzing a biological sample from a patient. The sample processing system comprises: a plurality of analyzers comprisingat least one mass spectrometer, wherein each analyzer in the plurality of analyzers is configured to acquire at least one measurement value corresponding to at least one characteristic of the biological sample; at least one data storage component which stores (i) a list of parameters for the plurality of analyzers, and (ii) at least two condition sets, which contain data associated with completingone or more test orders. The condition sets contain data which differ by at least one variable; and a control system operatively coupled to the plurality of analyzers, and the at least one data storage component. The control system is configured to (i) determine which condition set of the at least two condition sets to use based on the determined condition set, (ii) determine which analyzer or analyzers of the plurality of analyzers to use to process each test order based on the determined condition set and one or more parameters from the list of parameters, and (iii) cause the determined analyzer or analyzers to acquire one or more measurement values for the biological sample.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US Provisional Application 62 / 607,685, filed December 19, 2017, the contents of which are incorporated by reference in their entirety for all purposes. Background technique [0003] Mass spectrometry (MS) is an analytical technique used to determine the elemental composition of samples, quantify the mass of particles and molecules, and elucidate the chemical structure of molecules. Various types of MS with high specificity, such as liquid chromatography (LC-MS), gas chromatography (GC-MS), and matrix-assisted laser desorption / ionization / time-of-flight (MALDI-TOF MS) are increasingly for clinical diagnosis. These MS techniques overcome many of the limitations of immunoassays (eg, non-specific binding and cross-reactivity of analytes) and offer many advantages. [0004] To date, MS techniques have not been widely used clinically due to challenges including sample preparation, online ex...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/487G01N33/94G01N33/82G01N27/62G01N33/68
CPCG01N33/487G01N35/00871G01N35/1095G01N2035/00881H01J49/26G01N35/0092G01N2035/00564G01N33/48792G01N2035/00356G01N2035/0444
Inventor 阿伦·胡德松水谷贵行苏巴西什·普尔卡亚斯塔托马斯·W·罗斯科
Owner BECKMAN COULTER INC