Fixing device for positioning rat for intragastric administration operation

Abstract

The invention discloses a fixing device for positioning a rat for intragastric administration operation. The fixing device comprises a transparent tube body, wherein one end of the tube body is an inlet end, the other end of the tube body is an operation end, slide rails are arranged on the outer wall of the operation end of the tube body in the radial direction of the tube body, a positioning seat is slidably arranged on the slide rails, a positioning groove allowing the head of the rat to go out is formed in the positioning seat, clamping arms are arranged on the end surface of the positioning groove in a swing manner, the two clamping arms are staggered and mutually hinged, and hoop sleeves for tightening the clamping arms are arranged at the ends, away from the positioning groove, of the two clamping arms in a sleeving manner, a rotating through groove is formed in the positioning groove, an abutting cam is rotationally arranged in the rotating through groove, and a binding mechanism for fixing the body of the rat is also arranged on the tube body. The fixing device is simple in structure, can effectively position the fat and facilitates intragastric administration operation.

Description

technical field [0001] The invention relates to the technical field of animal experiments, in particular to a fixing device for rat gavage operation. Background technique [0002] Oral gavage administration is the most commonly used method of administration in animal experiments, and it is especially commonly used in multidisciplinary experimental animal modeling such as physiology, pharmacology, and immunity, as well as studies on drug toxicity, drug efficacy, and dose determination. The method is easy to operate, accurate in dosage, can be fed with solution or suspension, can be repeatedly administered, and is suitable for various experimental animals such as rats, rats, and rabbits. At present, during the gavage operation, the operator mainly grabs the rat with one hand and injects it with the other hand. By placing the rat on a rough surface, grasp the ear and head and neck skin with the thumb and forefinger of one hand, Clamp the tail with the palm of your hand and the...

AI Technical Summary

Problems solved by technology

At present, during the gavage operation, the operator mainly grabs the rat with one hand and injects it with the other hand. By placing the rat on a rough surface, grasp the ear and head and neck skin with the thumb and forefinger of one hand, Clamp the tail with the palm of your hand and the ring finger of your little finger so that the head, neck and body (mouth and esophagus) are in a straight line, with the abdomen facing up, and the other hand holds the syringe and inserts the needle into the mouth from one side of the mouth, avoiding the teeth, and tightening through the tongue. Slowly insert into the lower part of the esophagus along the upper palate, but during this process, the rat is prone to struggle, resulting in unsmooth injection, and making the needle tube easy to scratch the rat, which is not conducive to subsequent experimental operations. At the same time, when the rat struggles, the neck position will The function rotates, and it is easy to bite the operator, and the one-handed injection operation is also very inconvenient, which is not conducive to improving production and processing efficiency

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