Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Steroid compound and preparation method and application thereof

A compound and steroid technology, which is applied in the field of steroid compound preparation, can solve problems such as the destruction of open arrow resources and hindering the development and utilization of medicinal value

Active Publication Date: 2021-01-12
NORTHWEST A & F UNIV
View PDF6 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The uncontrolled excavation of roots and rhizomes has caused devastating damage to the perennial arrowhead resources. At present, in its main production areas, namely the Qinba Mountains and the Shennongjia forest area, the wild arrowhead resources have been significantly reduced, hindering its large-scale research. Large-scale development and utilization of medicinal value

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Steroid compound and preparation method and application thereof
  • Steroid compound and preparation method and application thereof
  • Steroid compound and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0045] The technical scheme of the present invention is described in more detail below in conjunction with accompanying drawing of specification sheet and specific experimental research, and the materials used in the following experiments are common items available on the market, and if there is no special instruction, the proportional relationship between the solvents is In terms of volume ratio; the concentration of the solution is the volume concentration; in the following experiments, the separation of each component is carried out. Unless otherwise specified, the name of each component is named according to the order of outflow, mobile phase flow or separation; Unless otherwise specified, the separation experimental methods adopted below are conventional experimental methods in the prior art.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a steroid compound and a preparation method and application thereof. The preparation method of the steroid compound comprises the following steps: by taking leaves of tupistrachinensis baker as an extraction raw material, carrying out alcohol extraction to obtain extract, and carrying out organic solvent extraction and column chromatography separation on the extract to obtain the steroid compound, wherein compounds 1-9 are steroid components, the compounds 1 and 4 are cardiac glycoside compounds, the compounds 2, 3, 5, 6 and 7 are spirostane type steroid saponin or sapogenin, and the compounds 8 and 9 are furostane type steroid saponin. An antibacterial activity research shows that the compound 3 has excellent antibacterial activity on bacillus subtilis (B.subtilii), staphylococcus aureus (S.aureus) and candida albicans (C.albicans). The invention preliminarily reveals the material basis of the antibacterial activity of selaginella tamariscina, and is of greatsignificance to the further design and development of new antibacterial drugs.

Description

technical field [0001] The invention belongs to the field of natural compounds, and in particular relates to a steroid compound, a preparation method and an application. Background technique [0002] Campylandra chinensis (Campylandra chinensis) is a perennial herb of the genus Campylandra in the family Asparagaceae. It has the functions of clearing heat and detoxifying, expelling wind and dampness, dissipating blood stasis and relieving pain. Carbuncle sores, poisonous snake bites, etc. Especially in the forest area of ​​Shennongjia, the root and rhizome slices of the dried arrowhead are often used as ingredients for making herbal tea and sold in large quantities. It has special effects on pharyngitis, sore throat, sore tongue, toothache, sore throat, anti-inflammatory and fire-dispersing . [0003] Folks often use the roots and rhizomes of Arrowhead as medicine, but the roots and rhizomes are mainly obtained by digging wild Arrowhead resources, and the leaves are often d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07J19/00C07J71/00A61K31/585A61K31/58A61P31/04A61P31/10
CPCC07J19/005C07J71/0005A61P31/04A61P31/10
Inventor 闫喜涛高锦明谢锦艳
Owner NORTHWEST A & F UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com