External traditional Chinese medicine composition for treating blepharitis and preparation method and application thereof

A composition and a technology for blepharitis, applied in the field of traditional Chinese medicine compositions, can solve the problems of complex drug composition, increased cost and the like, and achieve the effects of good safety and economic benefits, improved ocular foreign body sensation, and easy availability of raw materials

Active Publication Date: 2021-01-26
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this traditional Chinese medicine decoction has a good therapeutic effect on blepharitis, its drug composition is complex, including 8 raw materials such as Coptis chinensis, which increases the cost of drug preparation

Method used

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  • External traditional Chinese medicine composition for treating blepharitis and preparation method and application thereof
  • External traditional Chinese medicine composition for treating blepharitis and preparation method and application thereof
  • External traditional Chinese medicine composition for treating blepharitis and preparation method and application thereof

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Effect test

Embodiment 1

[0030] Embodiment 1 The preparation method of Chinese medicine composition of the present invention

[0031] Take 15g of sophora flavescens and 30g of mint, add 8 to 10 times the weight of water and decoct for 0.5 to 1 hour, then separate the medicinal liquid from the dregs, concentrate and refine the medicinal liquid, and obtain the extract powder by spray drying, and finally pass the dry powder Granulating, promptly obtains the traditional Chinese medicine composition granule of the present invention.

[0032] The method for refining the medicinal solution described in this embodiment is to filter the concentrated medicinal solution and then concentrate.

[0033] The method for refining the liquid medicine above can also adopt conventional refining methods in the field of traditional Chinese medicine, including water extraction and alcohol precipitation, adsorption clarification, macroporous adsorption resin adsorption, salting out, and dialysis.

Embodiment 2

[0034] Embodiment 2 The preparation method of Chinese medicine composition of the present invention

[0035] Get Sophora flavescens 15g, Mint 15g, preparation method is the same as embodiment 1.

Embodiment 3

[0036] Embodiment 3 The preparation method of Chinese medicine composition of the present invention

[0037] Get Sophora flavescens 30g, Mint 15g, preparation method is the same as embodiment 1.

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PUM

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Abstract

The invention provides an external traditional Chinese medicine composition for treating blepharitis and a preparation method and application thereof. The traditional Chinese medicine composition is apreparation prepared from the following raw material medicines in parts by weight: 10 to 60 parts of radix sophorae flavescentis and 10 to 40 parts of herba menthae. The traditional Chinese medicinecomposition provided by the invention has no toxic side effect and can be used for effectively treating the blepharitis; clinical verifications show that the traditional Chinese medicine composition provided by the invention can be used for remarkably improving symptoms including eye foreign body sensation, photophobia and lacrimation, burning sensation, eye itching and the like, and especially has a remarkable curative effect on the blepharitis caused by demodicid mites; and the traditional Chinese medicine composition has good safety and economic benefits and provides a new medicine selection for clinically treating the blepharitis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine compositions, and in particular relates to an external Chinese medicinal composition for treating blepharitis and its preparation method and application. Background technique [0002] Blepharitis is subacute or chronic inflammation of the eyelid surface, eyelash follicles, and their glandular tissues. Its etiology is complicated, generally related to bacterial infection, physical and chemical stimulation, refractive error, chronic conjunctivitis, epiphora, phoria, poor hygiene habits, and decreased body resistance. It is a common clinical eye disease. According to different clinical characteristics, it can be divided into three categories: scaly blepharitis, ulcerative blepharitis, and canthal blepharitis. Mild cases can cause eye irritation in patients, and severe cases can involve the meibomian glands and cornea and affect vision. In recent years, more and more studies have found th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61P27/02A61P33/14
CPCA61K36/489A61K36/534A61P27/02A61P33/14A61K2300/00
Inventor 李翔李运帆杨凤姣万婧雯易文华
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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